ID N2A9Y2_9FIRM Unreviewed; 454 AA.
AC N2A9Y2;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=tRNA nucleotidyltransferase (CCA-adding enzyme) {ECO:0008006|Google:ProtNLM};
GN ORFNames=C823_04707 {ECO:0000313|EMBL:EMZ21134.1};
OS Eubacterium plexicaudatum ASF492.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Eubacterium.
OX NCBI_TaxID=1235802 {ECO:0000313|EMBL:EMZ21134.1, ECO:0000313|Proteomes:UP000012589};
RN [1] {ECO:0000313|EMBL:EMZ21134.1, ECO:0000313|Proteomes:UP000012589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ASF492 {ECO:0000313|EMBL:EMZ21134.1,
RC ECO:0000313|Proteomes:UP000012589};
RX PubMed=24723722;
RA Wannemuehler M.J., Overstreet A.M., Ward D.V., Phillips G.J.;
RT "Draft genome sequences of the altered schaedler flora, a defined bacterial
RT community from gnotobiotic mice.";
RL Genome Announc. 2:e00287-e00214(2014).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the tRNA nucleotidyltransferase/poly(A)
CC polymerase family. {ECO:0000256|RuleBase:RU003953}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMZ21134.1}.
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DR EMBL; AQFT01000136; EMZ21134.1; -; Genomic_DNA.
DR RefSeq; WP_004067748.1; NZ_AQFT02000004.1.
DR AlphaFoldDB; N2A9Y2; -.
DR STRING; 1235802.C823_04707; -.
DR GeneID; 78438272; -.
DR PATRIC; fig|1235802.3.peg.4968; -.
DR eggNOG; COG0617; Bacteria.
DR HOGENOM; CLU_015961_3_1_9; -.
DR OrthoDB; 9805698at2; -.
DR Proteomes; UP000012589; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0031123; P:RNA 3'-end processing; IEA:UniProt.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR CDD; cd05398; NT_ClassII-CCAase; 1.
DR Gene3D; 1.10.246.80; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3090.10; cca-adding enzyme, domain 2; 1.
DR InterPro; IPR032810; CCA-adding_enz_C.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002646; PolA_pol_head_dom.
DR PANTHER; PTHR46173; CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR46173:SF1; CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL; 1.
DR Pfam; PF01743; PolyA_pol; 1.
DR Pfam; PF13735; tRNA_NucTran2_2; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81891; Poly A polymerase C-terminal region-like; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000012589};
KW RNA-binding {ECO:0000256|RuleBase:RU003953};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003953}.
FT DOMAIN 26..148
FT /note="Poly A polymerase head"
FT /evidence="ECO:0000259|Pfam:PF01743"
FT DOMAIN 300..443
FT /note="CCA-adding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13735"
SQ SEQUENCE 454 AA; 52862 MW; E1F3E6B85B08A5DE CRC64;
MKRINVEVPA PVNYIIQELE KCGHEVYMVG GCVRDSVLGR KPHDYDICTS ATPDEILKAF
PDEEIIPTGL QHGTVTILIN KEPFEVTTYR IDGDYSDNRR PDNVTFTKNL VEDLRRRDFT
INAMAYNPKT GLIDPFNGME DIKYKKIRCV GSAEDRFNED ALRILRAIRF EAQLGFAGLP
ETMFEIERQY DRLKNISIER INSEFCKIVA SEQFCVELVL YPNVFSLFIP ELKDLIGFQQ
NNPYHAYDVF DHTVHAIEKC ESDDLVVRLA VFFHDFGKPY SYQDGEDGIR HFKGHGKVSA
EITDSIMKRL RFDNETRNNV VELVYYHDAT FEVGNKYVKR WLNKIGEKQF RWLLEVRKAD
IKGQKPDYEE SRIEKINNIE NILEEILSEK SCFSLKDLAV NGNDVKEVMK LKEGKDIGYW
LNEILKRVID GELENNKDDL VYWMTGVRDG WIKF
//
