ID N4TF81_FUSC1 Unreviewed; 885 AA.
AC N4TF81;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Probable endonuclease LCL3 {ECO:0000256|ARBA:ARBA00013404};
DE AltName: Full=Probable endonuclease lcl3 {ECO:0000256|ARBA:ARBA00014651};
GN ORFNames=FOC1_g10014936 {ECO:0000313|EMBL:ENH61983.1};
OS Fusarium oxysporum f. sp. cubense (strain race 1) (Panama disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1229664 {ECO:0000313|EMBL:ENH61983.1, ECO:0000313|Proteomes:UP000016928};
RN [1] {ECO:0000313|Proteomes:UP000016928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 1 {ECO:0000313|Proteomes:UP000016928};
RA Fang X., Huang J.;
RT "Genome sequencing and comparative transcriptomics of race 1 and race 4 of
RT banana pathogen: Fusarium oxysporum f. sp. cubense.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000016928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 1 {ECO:0000313|Proteomes:UP000016928};
RX PubMed=24743270;
RA Guo L., Han L., Yang L., Zeng H., Fan D., Zhu Y., Feng Y., Wang G.,
RA Peng C., Jiang X., Zhou D., Ni P., Liang C., Liu L., Wang J., Mao C.,
RA Fang X., Peng M., Huang J.;
RT "Genome and Transcriptome Analysis of the Fungal Pathogen Fusarium
RT oxysporum f. sp. cubense Causing Banana Vascular Wilt Disease.";
RL PLoS ONE 9:E95543-E95543(2014).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR017179}.
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DR EMBL; KB731260; ENH61983.1; -; Genomic_DNA.
DR AlphaFoldDB; N4TF81; -.
DR STRING; 1229664.N4TF81; -.
DR VEuPathDB; FungiDB:FOC1_g10014936; -.
DR HOGENOM; CLU_005966_1_0_1; -.
DR OMA; EKTCCTV; -.
DR Proteomes; UP000016928; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016442; C:RISC complex; IEA:UniProtKB-UniRule.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-UniRule.
DR GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:InterPro.
DR CDD; cd00175; SNc; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 2.40.50.90; -; 5.
DR InterPro; IPR016685; Silence_cplx_Nase-comp_TudorSN.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR016071; Staphylococal_nuclease_OB-fold.
DR InterPro; IPR002999; Tudor.
DR PANTHER; PTHR12302; EBNA2 BINDING PROTEIN P100; 1.
DR PANTHER; PTHR12302:SF2; STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00565; SNase; 4.
DR Pfam; PF00567; TUDOR; 1.
DR PIRSF; PIRSF017179; RISC-Tudor-SN; 1.
DR SMART; SM00318; SNc; 4.
DR SMART; SM00333; TUDOR; 1.
DR SUPFAM; SSF50199; Staphylococcal nuclease; 5.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50830; TNASE_3; 4.
DR PROSITE; PS50304; TUDOR; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|PIRNR:PIRNR017179};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022759};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000016928};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 3..142
FT /note="TNase-like"
FT /evidence="ECO:0000259|PROSITE:PS50830"
FT DOMAIN 165..307
FT /note="TNase-like"
FT /evidence="ECO:0000259|PROSITE:PS50830"
FT DOMAIN 315..453
FT /note="TNase-like"
FT /evidence="ECO:0000259|PROSITE:PS50830"
FT DOMAIN 482..615
FT /note="TNase-like"
FT /evidence="ECO:0000259|PROSITE:PS50830"
FT DOMAIN 696..756
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT REGION 444..463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 613..642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 618..632
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 885 AA; 98561 MW; 05C799AF6B4263AC CRC64;
MSKTFIGNVK SVLSGDTLIL TSPKNPNNER TLSLAYVTAP HLKREGDEPF AFQSREYLRN
LVVGKPVQAT VLYTIPTSGR EFGTAQLQDG TNLPDELVKA GWLKVREDAG RKEESDEVLD
RLETLRQLEN KAKAEDKGLH VGVGGIIDVQ NDLGGPEFLK EWKGKTVDGI VERVLSGDRV
LMRLLLSEKK HVQPMTLIAG IRTPATERTL PSTGTTQPAE EYGNEARSFV ESRLLQREIK
VEIVGASAQG QLVATLIHPR GNIAEFLLQE GLARCNDFHS IMLGERMAAL RAAEKQAQSK
KLRLHKHHVA KTESGNQDAI VSKVIGADTI LVRNKAGTTE KRISISSVRG PRTTEPSESP
FREEAKEFLR QKLIGKHVRI SIDGNKPATE GYEAREVATV TEKNTNINLL LVENGWASVI
RHRKDDTDRA PNYDDLLAAQ EKAKEEKKGM WSGKPQKAKQ YTDLSENTQK AKIMLATLQR
QKKVPAIVDF CKAGSRFTIL IPRESVKLTM VLGGIRAPRA PRADGEGGEP FGKESLDLAN
RRCNQRDCEV DIHDMDKVGG FIGDLYINRE NFAKVLVEEG LASVHAYSAE KSGNAAELFT
AEKKAKEARK NLWQDWDPSQ DEEYEEENTA ETAPETEVSI DKKPTDYRDV VITNIDANGK
LKLQEIGKGT AALESLMSEF RRFHLDSKNN NPLKDAPKTG EYVSAKFSAD GQWYRARVRA
NDRSAKKSEV VYIDYGNSEK VPWSSLRALD QPKFGAQKLK AQAIDASLSF VQLPTGADYF
EDAIGFIYEL TENKRLVANF DFIDNKENLS YVTLYDTGSS GELPGPNDSI NKEVVAGGYG
MVPKKLKAWE RSKAFESTLK HLKEVESQAK DQRLGMWEYG DITED
//
