ID N4TIW3_FUSC1 Unreviewed; 983 AA.
AC N4TIW3;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Oxysterol-binding protein like protein 3 {ECO:0000313|EMBL:ENH62534.1};
GN ORFNames=FOC1_g10012768 {ECO:0000313|EMBL:ENH62534.1};
OS Fusarium oxysporum f. sp. cubense (strain race 1) (Panama disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1229664 {ECO:0000313|EMBL:ENH62534.1, ECO:0000313|Proteomes:UP000016928};
RN [1] {ECO:0000313|Proteomes:UP000016928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 1 {ECO:0000313|Proteomes:UP000016928};
RA Fang X., Huang J.;
RT "Genome sequencing and comparative transcriptomics of race 1 and race 4 of
RT banana pathogen: Fusarium oxysporum f. sp. cubense.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000016928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 1 {ECO:0000313|Proteomes:UP000016928};
RX PubMed=24743270;
RA Guo L., Han L., Yang L., Zeng H., Fan D., Zhu Y., Feng Y., Wang G.,
RA Peng C., Jiang X., Zhou D., Ni P., Liang C., Liu L., Wang J., Mao C.,
RA Fang X., Peng M., Huang J.;
RT "Genome and Transcriptome Analysis of the Fungal Pathogen Fusarium
RT oxysporum f. sp. cubense Causing Banana Vascular Wilt Disease.";
RL PLoS ONE 9:E95543-E95543(2014).
CC -!- SIMILARITY: Belongs to the OSBP family.
CC {ECO:0000256|ARBA:ARBA00008842}.
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DR EMBL; KB731259; ENH62534.1; -; Genomic_DNA.
DR AlphaFoldDB; N4TIW3; -.
DR STRING; 1229664.N4TIW3; -.
DR TCDB; 2.D.1.1.6; the pi4p/ps counter transporter (p/p-ct) family.
DR VEuPathDB; FungiDB:FOC1_g10012768; -.
DR HOGENOM; CLU_007105_4_0_1; -.
DR OMA; SYFVRWV; -.
DR Proteomes; UP000016928; Unassembled WGS sequence.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR CDD; cd13289; PH_Osh3p_yeast; 1.
DR Gene3D; 2.40.160.120; -; 1.
DR Gene3D; 3.30.70.3490; -; 1.
DR Gene3D; 2.60.120.680; GOLD domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR009038; GOLD_dom.
DR InterPro; IPR036598; GOLD_dom_sf.
DR InterPro; IPR037239; OSBP_sf.
DR InterPro; IPR000648; Oxysterol-bd.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041680; PH_8.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR10972:SF216; OXYSTEROL-BINDING PROTEIN HOMOLOG 3; 1.
DR PANTHER; PTHR10972; OXYSTEROL-BINDING PROTEIN-RELATED; 1.
DR Pfam; PF01237; Oxysterol_BP; 1.
DR Pfam; PF15409; PH_8; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF144000; Oxysterol-binding protein-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF101576; Supernatant protein factor (SPF), C-terminal domain; 1.
DR PROSITE; PS50866; GOLD; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Reference proteome {ECO:0000313|Proteomes:UP000016928};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 1..142
FT /note="GOLD"
FT /evidence="ECO:0000259|PROSITE:PS50866"
FT DOMAIN 210..304
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 52..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 149..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 364..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 436..456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 525..579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 903..930
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 52..71
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..174
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..393
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 534..548
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 983 AA; 107977 MW; 15672DB936381EDA CRC64;
MAGIEQLESY IVRWVKVDEG NTLSWSVQPH KKSINFGIVK HPGSGATTFA SSTAEDLNNG
TEESGGTSDG KSARFSKKDT NAQELLKSKG FIPIKWIGKC EADKVSIGTY EVNHDQSGMY
GLVFDNTFSK QTSKTATFVV MTYPTGAPPQ TSSHLPNLQA PKAGASQTSL GRHSSPKLDG
VASASLDSLH SHNAVANANS ISGRSEVGSG NYHVGVLHKR RRKKGQGYAR RFFSLDYSTC
TLSYYYNPKS SALRGAIPLS LAAIAADERR REISIDSGAE VWHLRAPNDK EFQDWAHALE
KASRVARGLE TLDLPKNDHL KINTRQLQPI HQSSPQEDRE WEQVESLVSR VVGTRDALRR
LTREVTAQAK PPPVTSPQYL SPGAATSAID ENDTYFTPPP EQRRSFWRRK SNTPAISPAT
LGAPTALAVP APGGVTTTIS ANMPNHSRRQ SKGLVREENS LQDHCQSLLT DLDSVVSEFT
ALINNSKRRR MPVPLSAGGV SRKSIDTVST ADEFFDAEDA NSAVLKIDGS EDEASRSEEA
EDEEEDSFRD NSSVSSIGEN DTANLDDASH LFPTKPKSLT PLPIEQAVTR RSTIPPAAAP
APSLIAFFRK NVGKDFSTIS MPVTSNEPSS MCQKVAEQLE YAQLLNQAAK QSSPTDRLLF
VAAFAVSQFS SGRAKERAIR KPFTPLLGET FELVRSEKEV PGGFRLLVEK VQHRPLLLAM
QADSANWSFS QSPAPGQKFW GKSAEITTDG RVRIVLRLSN GSEERYSWNI ATMFLRNVVM
GEKYVEPVGT MHVVNDSTGH KAAVEFKSKG MWGGRIEDVS VEIFNPEGVN TGSGLVGTWT
NSLKTTGKGG GQEIWRVGPL VENAAQTFGL TTFAASLNEV TEIEKGKLPP TDCRLRPDQR
AYEQGAIDDA EDLKQKLEEA QRGRRRELEE RGETYKPRWF VKVENAPEGE EVWKLKTGKD
SYWEERAKGS WQGVEDLFKV TDD
//
