ID N4U1Q2_FUSC1 Unreviewed; 588 AA.
AC N4U1Q2;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=5'-nucleotidase {ECO:0000313|EMBL:ENH65347.1};
GN ORFNames=FOC1_g10005880 {ECO:0000313|EMBL:ENH65347.1};
OS Fusarium oxysporum f. sp. cubense (strain race 1) (Panama disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1229664 {ECO:0000313|EMBL:ENH65347.1, ECO:0000313|Proteomes:UP000016928};
RN [1] {ECO:0000313|Proteomes:UP000016928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 1 {ECO:0000313|Proteomes:UP000016928};
RA Fang X., Huang J.;
RT "Genome sequencing and comparative transcriptomics of race 1 and race 4 of
RT banana pathogen: Fusarium oxysporum f. sp. cubense.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000016928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 1 {ECO:0000313|Proteomes:UP000016928};
RX PubMed=24743270;
RA Guo L., Han L., Yang L., Zeng H., Fan D., Zhu Y., Feng Y., Wang G.,
RA Peng C., Jiang X., Zhou D., Ni P., Liang C., Liu L., Wang J., Mao C.,
RA Fang X., Peng M., Huang J.;
RT "Genome and Transcriptome Analysis of the Fungal Pathogen Fusarium
RT oxysporum f. sp. cubense Causing Banana Vascular Wilt Disease.";
RL PLoS ONE 9:E95543-E95543(2014).
CC -!- SIMILARITY: Belongs to the 5'-nucleotidase family.
CC {ECO:0000256|ARBA:ARBA00006654, ECO:0000256|RuleBase:RU362119}.
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DR EMBL; KB730496; ENH65347.1; -; Genomic_DNA.
DR AlphaFoldDB; N4U1Q2; -.
DR STRING; 1229664.N4U1Q2; -.
DR VEuPathDB; FungiDB:FOC1_g10005880; -.
DR HOGENOM; CLU_005854_7_1_1; -.
DR OMA; NYDCDSP; -.
DR Proteomes; UP000016928; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0009166; P:nucleotide catabolic process; IEA:InterPro.
DR CDD; cd07409; MPP_CD73_N; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 3.90.780.10; 5'-Nucleotidase, C-terminal domain; 1.
DR InterPro; IPR008334; 5'-Nucleotdase_C.
DR InterPro; IPR036907; 5'-Nucleotdase_C_sf.
DR InterPro; IPR006179; 5_nucleotidase/apyrase.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR PANTHER; PTHR11575:SF24; 5'-NUCLEOTIDASE; 1.
DR PANTHER; PTHR11575; 5'-NUCLEOTIDASE-RELATED; 1.
DR Pfam; PF02872; 5_nucleotid_C; 1.
DR Pfam; PF00149; Metallophos; 1.
DR PRINTS; PR01607; APYRASEFAMLY.
DR SUPFAM; SSF55816; 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU362119};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU362119};
KW Reference proteome {ECO:0000313|Proteomes:UP000016928};
KW Signal {ECO:0000256|RuleBase:RU362119}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|RuleBase:RU362119"
FT CHAIN 19..588
FT /evidence="ECO:0000256|RuleBase:RU362119"
FT /id="PRO_5005142061"
FT DOMAIN 40..253
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 340..501
FT /note="5'-Nucleotidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02872"
FT REGION 539..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 588 AA; 64306 MW; C8408868E5DFBDB9 CRC64;
MKSSITLGAL ALAGLVSAED VLYSKRLNKR FVDDDGHYNM SFFHVNDVHA HLDEFAKSGT
DCVDPKKGCF GGYARIKHTV DGLRKDHPDN LWLNAGDEFQ GTLFYSFYGP SKIAENLNTL
KFDAMTLGNH EWDGGDEELG EFLQNLTFPV VSCNVKSEYE GLNKTIKNYQ IFKEHDLAVI
GVTTDTTPGI SSVGNKTTFL DPITEVQKSI WEIRNKTDIN RIVALTHIGY DVDKELAAKT
EGLSLIIGGH SHTLLGDMEK AEGDYPTIVK DINGDEVFIV TAYRWGEYLG SIDLTFDKDG
KALEYHGAPI HLTNQTEMDK TLNKTIKGWR GPFEKFAAEV VGNTKAELDQ STCQEGDCLL
GQVMADAMLE YRLNQSRNDD DKPAFAFINA GGVRATIDEG NITRGEVLTS FPFGNAIVEL
TFTGAELKEV FEGAVTGVNQ KNKKEITSWF QVSKGLKIEY NPDNKNGSKL VNATLNGEAF
EDKTKYRVVT LDFLAGGGDN FFSIDAKNLA TLDSQDEVLI GYLDAHNPLD PKLEERVVET
NATSSEDAEQ GEAKGKGGSA GGDGNAASGV HASILSAVFG VAMVLFMM
//
