ID N4UCR0_FUSC1 Unreviewed; 1569 AA.
AC N4UCR0;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Guanine nucleotide exchange factor LTE1 {ECO:0000313|EMBL:ENH73004.1};
GN ORFNames=FOC1_g10009740 {ECO:0000313|EMBL:ENH73004.1};
OS Fusarium oxysporum f. sp. cubense (strain race 1) (Panama disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1229664 {ECO:0000313|EMBL:ENH73004.1, ECO:0000313|Proteomes:UP000016928};
RN [1] {ECO:0000313|Proteomes:UP000016928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 1 {ECO:0000313|Proteomes:UP000016928};
RA Fang X., Huang J.;
RT "Genome sequencing and comparative transcriptomics of race 1 and race 4 of
RT banana pathogen: Fusarium oxysporum f. sp. cubense.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000016928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 1 {ECO:0000313|Proteomes:UP000016928};
RX PubMed=24743270;
RA Guo L., Han L., Yang L., Zeng H., Fan D., Zhu Y., Feng Y., Wang G.,
RA Peng C., Jiang X., Zhou D., Ni P., Liang C., Liu L., Wang J., Mao C.,
RA Fang X., Peng M., Huang J.;
RT "Genome and Transcriptome Analysis of the Fungal Pathogen Fusarium
RT oxysporum f. sp. cubense Causing Banana Vascular Wilt Disease.";
RL PLoS ONE 9:E95543-E95543(2014).
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DR EMBL; KB730092; ENH73004.1; -; Genomic_DNA.
DR STRING; 1229664.N4UCR0; -.
DR VEuPathDB; FungiDB:FOC1_g10009740; -.
DR HOGENOM; CLU_001471_0_0_1; -.
DR OMA; ICNYATM; -.
DR Proteomes; UP000016928; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd06224; REM; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF364; GUANINE NUCLEOTIDE EXCHANGE FACTOR LTE1; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR SMART; SM00147; RasGEF; 1.
DR SMART; SM00229; RasGEFN; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000016928}.
FT DOMAIN 186..313
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 1322..1566
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 1..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 398..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 472..492
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 647..669
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 740..765
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 796..887
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1074..1129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1173..1196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1223..1246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..37
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..57
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..118
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 802..830
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 843..873
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1089..1114
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1225..1241
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1569 AA; 173044 MW; EBA8C09CBF1038F9 CRC64;
MEALESSTSA DPLTPASGLS APPPVPVPIP SPPPAATTVK DPLSTKSKDQ SRSRSGSGAI
AVAAPNVTAA GAALKKKENT SPGFSTPKRR IHQKKPTTRS LKDSDSSLDN QGSLSRWEIT
PDGGSAGREG RQFTVANVGN NGRIYLRPTV RPAYQRTPQP QFVFPITPPS TAGLDAISSK
QLQDETSELH VTATPPRLVA EITSPSFLDY ELISDFFLTF RAFLEPVDLL RMLIARLRWA
LARDDETGMV VRVRTFVALR HWILNYFMDD FVVDYNLRQT FCELLNDFVD ELSQCNRSRK
VQLKILGELK KCWRRVCALY WDGPNFDDTL DSSVPITPGG IAGHRDPSLD PSFWDRDDGE
TPRIESLLPL RRSPAERTSF IADVSRAGHV GDSVVVEHRP STPERQTARD SAEQQTSPIS
MTSMDIISCS FPSKIKPAQP HQTNPLGAHP VSTSGYHTGP VATTPRALVG KRVRPQAAHK
RNNSLTDSLR EHSTDKLSFK DQEFMMTAPY GGSLVRGNLL PPGQAFVDVE PDEFSTSLVP
SPNLHPESRS LVKERIPAGA MSGHGMKKLL GTVRRALSTR GQGMSPTQGS LVSLGNIGPR
GAVTNRIPGT AVVPQSRHRP NGARPTVRID LLGAEIVEDF KKAVRDEAAA EADRRGLPPP
MSPNPSLTPT RDFHYSAAHM DTTTYDHITH EHRHRPVSDM AITTGSKSIV IVDDTTPFDP
SLLHRIPNSN ASVEAFADTF KLTGGDPTPP STPPAGNGGN TPRRSSYLLN QHVVRPSLDE
DPLPPFVPDF ETLAPVTSAP MSEDGSRVSY STAARSTRNR PPVSYQNHQR NKSGRTHRSL
NSILRRRSSF TNGLARRSTV QSFDATTVSA QSIAEPEPEE PMPPPLRILR RRPGGDLRAA
TNVGELDPVT LRRSQSVGSL TTYSESIRGS FMQSPRVASF GRGSFGQGSV VSIEYVQPRS
EAFSVGQLAD KPKRELSLFS THSSKPAMRP SFEKEAQKLA QIPDDDDDGG IESALAKLEG
KLPEKKSHKS AVSLQAPPQT IGEVILASAQ SEVDRKRNHH EQELMVRETF MLDPEDSEPE
PLIEPQEQNL SPERPTTEAR SFLTGSSRES YSSVPILDRD SAKGRPWTNM SILEGSDEET
TPRPHKTVLY TEDGGDSQHA SYDFIEKTRS IEGIKPGNTA PSVDEDQSFL DDDSDLSSEM
SAEALEYDDS EYGDGILPRV KLPAHPLGSP APPPNRKPPS PPMTLVQALE MSPPHCFKVP
ELHEDQVWGQ KPLPPTPETT PTAAYVQTAD QTSADALRQV AKVNSFESNK YSAHLPFILA
FDSEILAQQF TLIEKDALNE IDWKELIDMN WKDAAHSDSR SWVDFLRNSD AHGVEVVIAR
FNIMVKWAIS EIVLTQGLEE RVRCITKYIH IATHCRRYRN FATLAQLTIA LSSNEVARLT
KTWQHVAPQD LKTLQDLEKL VTPMRNFYNL RAEMEVGSDQ GCIPFVGIYT HDLLYNAQRP
SEMAGSPTTP PLINFERCRI AASVVKTLLR LLEASTRYKF QPIEGITERC LWMSALSDED
IRRHSEMLE
//
