ID N4UHW0_FUSC1 Unreviewed; 518 AA.
AC N4UHW0;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Nuclear fusion protein KAR5 {ECO:0008006|Google:ProtNLM};
GN ORFNames=FOC1_g10011947 {ECO:0000313|EMBL:ENH69590.1};
OS Fusarium oxysporum f. sp. cubense (strain race 1) (Panama disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1229664 {ECO:0000313|EMBL:ENH69590.1, ECO:0000313|Proteomes:UP000016928};
RN [1] {ECO:0000313|Proteomes:UP000016928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 1 {ECO:0000313|Proteomes:UP000016928};
RA Fang X., Huang J.;
RT "Genome sequencing and comparative transcriptomics of race 1 and race 4 of
RT banana pathogen: Fusarium oxysporum f. sp. cubense.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000016928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 1 {ECO:0000313|Proteomes:UP000016928};
RX PubMed=24743270;
RA Guo L., Han L., Yang L., Zeng H., Fan D., Zhu Y., Feng Y., Wang G.,
RA Peng C., Jiang X., Zhou D., Ni P., Liang C., Liu L., Wang J., Mao C.,
RA Fang X., Peng M., Huang J.;
RT "Genome and Transcriptome Analysis of the Fungal Pathogen Fusarium
RT oxysporum f. sp. cubense Causing Banana Vascular Wilt Disease.";
RL PLoS ONE 9:E95543-E95543(2014).
CC -!- FUNCTION: Required for nuclear membrane fusion during karyogamy.
CC {ECO:0000256|ARBA:ARBA00003389}.
CC -!- SIMILARITY: Belongs to the KAR5 family.
CC {ECO:0000256|ARBA:ARBA00010473}.
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DR EMBL; KB730216; ENH69590.1; -; Genomic_DNA.
DR AlphaFoldDB; N4UHW0; -.
DR VEuPathDB; FungiDB:FOC1_g10011947; -.
DR HOGENOM; CLU_039421_0_0_1; -.
DR OMA; MKSSPSC; -.
DR Proteomes; UP000016928; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0000742; P:karyogamy involved in conjugation with cellular fusion; IEA:InterPro.
DR GO; GO:0048288; P:nuclear membrane fusion involved in karyogamy; IEA:InterPro.
DR InterPro; IPR007292; Nuclear_fusion_Kar5.
DR PANTHER; PTHR28012; NUCLEAR FUSION PROTEIN KAR5; 1.
DR PANTHER; PTHR28012:SF1; NUCLEAR FUSION PROTEIN KAR5; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Karyogamy {ECO:0000256|ARBA:ARBA00022459};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000016928};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..518
FT /note="Nuclear fusion protein KAR5"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004120985"
FT COILED 381..408
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 518 AA; 57396 MW; AD6934A9DA4FE57B CRC64;
MSSKAMSFFL LGVTFLTVFA TEAHCFSWRP RPADGMFEDA NITTVGHQVT LQHPQRSSDN
SALLNKQSEK RLSNVYTTAL QELQDLESEP LCHRIAARLL VNNCHLLDSQ DDAKVHIDSG
RAARDFVDSY AASLAICDLE RGSFRIPVSC SKFRESTLAT LSASPIPQIH VSTVEIDECL
EGLAQSDSAW NTWVSYRHKA LRFCDAARAD HQKDENILLY QKITKILEKL TRDIEADMEE
RFHSLNRAYT AASQSVEDIG PHVRHLRTEM ERASQILRDD LGRAAQDSRD VVESGLKETK
VLHDLLELLA RSVQEKTADI VSSQEVALQT STKQLNNEVD ILMAVLSAAI SSSVSLQNQV
ELTESRNADI LEKQVKIEQG MGKLEELAED LLVKYDNHES RLDKAFRKTG QVLDILDATA
ASATGLQSSV FSSFGLSGVW PYIICPFLSL AMGSYGLEPS LVRNIWLVGF GELMGMVVSK
ADSYKDAFGF PSTVETPDLT LNDTFNTSLA GESILKSV
//
