ID N4UI99_FUSC1 Unreviewed; 1299 AA.
AC N4UI99;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=CAP-Gly domain-containing protein {ECO:0000259|PROSITE:PS50245};
GN ORFNames=FOC1_g10014302 {ECO:0000313|EMBL:ENH68516.1};
OS Fusarium oxysporum f. sp. cubense (strain race 1) (Panama disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1229664 {ECO:0000313|EMBL:ENH68516.1, ECO:0000313|Proteomes:UP000016928};
RN [1] {ECO:0000313|Proteomes:UP000016928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 1 {ECO:0000313|Proteomes:UP000016928};
RA Fang X., Huang J.;
RT "Genome sequencing and comparative transcriptomics of race 1 and race 4 of
RT banana pathogen: Fusarium oxysporum f. sp. cubense.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000016928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 1 {ECO:0000313|Proteomes:UP000016928};
RX PubMed=24743270;
RA Guo L., Han L., Yang L., Zeng H., Fan D., Zhu Y., Feng Y., Wang G.,
RA Peng C., Jiang X., Zhou D., Ni P., Liang C., Liu L., Wang J., Mao C.,
RA Fang X., Peng M., Huang J.;
RT "Genome and Transcriptome Analysis of the Fungal Pathogen Fusarium
RT oxysporum f. sp. cubense Causing Banana Vascular Wilt Disease.";
RL PLoS ONE 9:E95543-E95543(2014).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the dynactin 150 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00011010}.
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DR EMBL; KB730248; ENH68516.1; -; Genomic_DNA.
DR STRING; 1229664.N4UI99; -.
DR VEuPathDB; FungiDB:FOC1_g10014302; -.
DR HOGENOM; CLU_002523_1_1_1; -.
DR OMA; LFEMEPV; -.
DR Proteomes; UP000016928; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1170.10; -; 1.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR022157; Dynactin.
DR PANTHER; PTHR18916; DYNACTIN 1-RELATED MICROTUBULE-BINDING; 1.
DR PANTHER; PTHR18916:SF6; DYNACTIN SUBUNIT 1; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR Pfam; PF12455; Dynactin; 1.
DR SMART; SM01052; CAP_GLY; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR PROSITE; PS00845; CAP_GLY_1; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000016928}.
FT DOMAIN 24..66
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT REGION 77..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1007..1143
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 126..177
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 242..257
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..310
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1299 AA; 144928 MW; A302F008296D9BC9 CRC64;
MPDFKPGQTV QLNDGSKAIV RFVGTTHFQV GEWIGVELEN KTGKNDGSVQ GERYFDCPMG
YGMFVKPVMA KIIAQAPTPK PAARKPAARP SSFAPTSGRA SSAAGDAGLG RRKSLNAPSP
SPVPRVSRPT SIARSPTKSP TKQLSAASST TVSRTGTPSN ARAPSVGAKS RQSIGGPRTS
MGPPPPTART RQASTSSGTA RAASVAPRTT TSRMSLAGPP RPASRPASRP SSAARRTSVD
SQARRGSSDR DDIASPIKDN GDILSPQPRS PVQARTKALE KLTGGPSSRT TTPPAARKPS
STTTGPRPAA STAASREIED LKAKLKVLER KRAEDRDKLK QLDKVQGERD KFESVIQMLQ
QKYQPQQQEN AELKKLLKEA EMRLDSVEEL QAEHDSILEL ATLDREMAEE TAEVLKAELE
ALKEKAEEME LEVEILREEN EEYSKGMAPE ERASSGWLQM ERANERLKEA LMRLRDLTQE
TEEELKGQIK GLEEDVKEFN TMKEEFSKCR GKLEQSESAV EDLRQQLDNA LGAEDMIEDL
TERNMSMSEQ IEELKAVIDD LESLKEINDE LEINHVQNEK EMQEELDFKD SVIAEQARRA
AQQEESLEDM EYTLSRFREL VTSLQSDLDD MKASQAVTEG ESEKLNDRSR AMMDLNMKLQ
ISASKAQVKT IDLELRRLDA QEAEQHLEIV KLFLPDTYKE DQDSVLSLLR FRRVAFKANL
LNSFIRERLN GQPHPGHEDD VFAGCDASDK LVWVSTMCDR FVSDMTHCTI EQFSKYQNAL
HELEPVERAL NVWIDGLRRD DLKEKTCADE LHRTIALLSH LGEPPRLRSR LLYHREGEED
ELAQHFAKKS EAVVTHTRGT KVIAAKAVRA LQDLRTRSLS LLPDTNEAFE QCCEATQELA
DLARQIGLGI HSLFTADEGR TEPFSYAEVQ TAVYKTVLSV STSSESDLFS TYLSKLRAVT
TQISDLVSLA TDLDQVQEFD VTPAPWRLRS QELKALKTIP VDAEEELRRL KEEHSEARRT
IAQRDEHLST AVLKIETLES RMRDAQANID RIAKLQEELE ASGQQIGSLK EDIEKQDREL
KNLESERDKW KKIASDSRAY ADGADAAGAK AGQERAVATA REMDALKKDI ESLQSAVRYL
REDNRRARTS EQHKYEWLAE PLKKPTSVAE KRRNMIAAEG KDVLGELVKM ASSASLYDFA
SLPQDKLAWK PVRSTPQYHA AKQMEDYASW ESWQESVLKK AHVLQGQTAN AERRKKTPTA
ARLRIKLPGV DGKVVPGSGR GVQIVGSQEW EALQGRLAV
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