ID N4ULC6_FUSC1 Unreviewed; 457 AA.
AC N4ULC6;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=mannan endo-1,4-beta-mannosidase {ECO:0000256|ARBA:ARBA00012706};
DE EC=3.2.1.78 {ECO:0000256|ARBA:ARBA00012706};
GN ORFNames=FOC1_g10006524 {ECO:0000313|EMBL:ENH72152.1};
OS Fusarium oxysporum f. sp. cubense (strain race 1) (Panama disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1229664 {ECO:0000313|EMBL:ENH72152.1, ECO:0000313|Proteomes:UP000016928};
RN [1] {ECO:0000313|Proteomes:UP000016928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 1 {ECO:0000313|Proteomes:UP000016928};
RA Fang X., Huang J.;
RT "Genome sequencing and comparative transcriptomics of race 1 and race 4 of
RT banana pathogen: Fusarium oxysporum f. sp. cubense.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000016928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 1 {ECO:0000313|Proteomes:UP000016928};
RX PubMed=24743270;
RA Guo L., Han L., Yang L., Zeng H., Fan D., Zhu Y., Feng Y., Wang G.,
RA Peng C., Jiang X., Zhou D., Ni P., Liang C., Liu L., Wang J., Mao C.,
RA Fang X., Peng M., Huang J.;
RT "Genome and Transcriptome Analysis of the Fungal Pathogen Fusarium
RT oxysporum f. sp. cubense Causing Banana Vascular Wilt Disease.";
RL PLoS ONE 9:E95543-E95543(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Random hydrolysis of (1->4)-beta-D-mannosidic linkages in
CC mannans, galactomannans and glucomannans.; EC=3.2.1.78;
CC Evidence={ECO:0000256|ARBA:ARBA00001678};
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DR EMBL; KB730104; ENH72152.1; -; Genomic_DNA.
DR AlphaFoldDB; N4ULC6; -.
DR STRING; 1229664.N4ULC6; -.
DR VEuPathDB; FungiDB:FOC1_g10006524; -.
DR HOGENOM; CLU_031603_4_0_1; -.
DR OMA; RTWAFHD; -.
DR Proteomes; UP000016928; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0030248; F:cellulose binding; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR035971; CBD_sf.
DR InterPro; IPR000254; Cellulose-bd_dom_fun.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR045053; MAN-like.
DR PANTHER; PTHR31451; MANNAN ENDO-1,4-BETA-MANNOSIDASE 7; 1.
DR PANTHER; PTHR31451:SF21; MANNAN ENDO-1,4-BETA-MANNOSIDASE C; 1.
DR Pfam; PF00734; CBM_1; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR SMART; SM00236; fCBD; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF57180; Cellulose-binding domain; 1.
DR PROSITE; PS00562; CBM1_1; 1.
DR PROSITE; PS51164; CBM1_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016928};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..457
FT /note="mannan endo-1,4-beta-mannosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004121909"
FT DOMAIN 421..457
FT /note="CBM1"
FT /evidence="ECO:0000259|PROSITE:PS51164"
FT REGION 387..419
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..419
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 457 AA; 50100 MW; 38C9BD7BCDA04DD0 CRC64;
MKFASIVAAA FASAPALAVP AGFVTTDGTK FQLDGKDFFF AGSNAYYLPF NVWGTDHYAD
VKLGLQLAKD AGLKVMRTWA FHDNNRTYVS GGLPQYGTGA ENTVMQFFEK DGSVKIDLSK
LDVVIEAAEA TNMKLILALT NNWADYGGMD VYTVNLGGRY HDDFYRLPAI KKAFKNYISA
VVNRYKDSPA VFAWEIANEP RCGADGTRNL PRGPDCTPAT ITSWVSEMST YIKSLDPNHL
VTTGSEGGFN RQSDDWTYNG ADGTDFDAEI KLPNIDFNTF HSYPQYWSKT TDWVVQWIKD
HAAAGATAKK PVLHEEYGWT DKSTRIATLS KWQKASLDLE VSDMYWQFGT SKFSYGKNHD
DGNTIYLEDD EAQPLVYEHA AAVNAANGGA APTKPTTTAT ATSKPSTTLS TTSKPTVTGG
PTVPRYGQCG GASWTGPTVC ASPYTCKEQN QWYSQCL
//
