ID   N6UEY6_DENPD            Unreviewed;        87 AA.
AC   N6UEY6;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   03-MAY-2023, entry version 41.
DE   RecName: Full=KASH domain-containing protein {ECO:0000259|PROSITE:PS51049};
DE   Flags: Fragment;
GN   ORFNames=D910_12058 {ECO:0000313|EMBL:ERL94784.1}, YQE_03308
GN   {ECO:0000313|EMBL:ENN80315.1};
OS   Dendroctonus ponderosae (Mountain pine beetle).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC   Curculionidae; Scolytinae; Dendroctonus.
OX   NCBI_TaxID=77166 {ECO:0000313|EMBL:ENN80315.1};
RN   [1] {ECO:0000313|Proteomes:UP000019118, ECO:0000313|Proteomes:UP000030742}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA   Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA   Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA   Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA   Birol I., Jones S.J., Bohlmann J.;
RT   "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT   a major forest pest.";
RL   Genome Biol. 14:R27-R27(2013).
RN   [2] {ECO:0000313|EnsemblMetazoa:ENN80315}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (JAN-2017) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the nesprin family.
CC       {ECO:0000256|ARBA:ARBA00008619}.
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DR   EMBL; APGK01024809; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KB740562; ENN80315.1; -; Genomic_DNA.
DR   EMBL; KB632399; ERL94784.1; -; Genomic_DNA.
DR   AlphaFoldDB; N6UEY6; -.
DR   STRING; 77166.N6UEY6; -.
DR   EnsemblMetazoa; ENN80315; ENN80315; YQE_03308.
DR   HOGENOM; CLU_2485616_0_0_1; -.
DR   Proteomes; UP000019118; Unassembled WGS sequence.
DR   Proteomes; UP000030742; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005635; C:nuclear envelope; IEA:UniProt.
DR   InterPro; IPR012315; KASH.
DR   Pfam; PF10541; KASH; 1.
DR   SMART; SM01249; KASH; 1.
DR   PROSITE; PS51049; KASH; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW   ProRule:PRU00385}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030742};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW   ProRule:PRU00385};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TOPO_DOM        1..41
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00385"
FT   TRANSMEM        44..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TOPO_DOM        63..87
FT                   /note="Perinuclear space"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00385"
FT   DOMAIN          33..87
FT                   /note="KASH"
FT                   /evidence="ECO:0000259|PROSITE:PS51049"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..32
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ENN80315.1"
SQ   SEQUENCE   87 AA;  9974 MW;  1344EE5C272D2EF3 CRC64;
     MPVNSRQKEK STGDKSAKPD GGDDDPGNDP ENTRWFKRLF KASLAFQLVI LTFVCLSCLY
     EPQCCDYMNN YQWSVSPKLH YEGRPPI
//