ID N6UJR9_DENPD Unreviewed; 1218 AA.
AC N6UJR9;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Myosin motor domain-containing protein {ECO:0000259|PROSITE:PS51456};
DE Flags: Fragment;
GN ORFNames=D910_05064 {ECO:0000313|EMBL:ERL87674.1}, YQE_01696
GN {ECO:0000313|EMBL:ENN81985.1};
OS Dendroctonus ponderosae (Mountain pine beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Curculionidae; Scolytinae; Dendroctonus.
OX NCBI_TaxID=77166 {ECO:0000313|EMBL:ENN81985.1};
RN [1] {ECO:0000313|Proteomes:UP000019118, ECO:0000313|Proteomes:UP000030742}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA Birol I., Jones S.J., Bohlmann J.;
RT "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT a major forest pest.";
RL Genome Biol. 14:R27-R27(2013).
RN [2] {ECO:0000313|EnsemblMetazoa:ENN81985}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JAN-2017) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; APGK01017248; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB739998; ENN81985.1; -; Genomic_DNA.
DR EMBL; KB631984; ERL87674.1; -; Genomic_DNA.
DR AlphaFoldDB; N6UJR9; -.
DR STRING; 77166.N6UJR9; -.
DR EnsemblMetazoa; ENN81985; ENN81985; YQE_01696.
DR HOGENOM; CLU_000192_7_2_1; -.
DR OMA; MIDHEFE; -.
DR Proteomes; UP000019118; Unassembled WGS sequence.
DR Proteomes; UP000030742; Unassembled WGS sequence.
DR GO; GO:0071944; C:cell periphery; IEA:UniProt.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd21759; CBD_MYO6-like; 1.
DR CDD; cd01382; MYSc_Myo6; 1.
DR CDD; cd21958; MyUb_Myo6; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.30.70.1590; -; 1.
DR Gene3D; 6.10.220.10; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 2.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR049016; MYO6_lever.
DR InterPro; IPR032412; Myosin-VI_CBD.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR036114; MYSc_Myo6.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF745; UNCONVENTIONAL MYOSIN-VI; 1.
DR Pfam; PF21521; MYO6_lever; 1.
DR Pfam; PF16521; Myosin-VI_CBD; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 1.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000030742}.
FT DOMAIN 41..753
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 630..652
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 921..948
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1018..1043
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1018..1040
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 137..144
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ENN81985.1"
SQ SEQUENCE 1218 AA; 139943 MW; 7641F46672A05482 CRC64;
MDETVWARDH KEGFVLGRIS EITPDGAEVI PLDPKFAKKV LPFSDIFRAN VVKGKDYDDN
CKIGLKLILR YFQSYVANIL IAVNPYKDIP ELYATKTIKA YQGKSLGELP PHVFAIADKA
FRDMRVFKQS QSIIVSGESG AGKTESTKHL LKYLCEGGGA GPIEQKILDA NPVLEAFGNA
KTTRNNNSSR FGKFIEVHFD KKFQVAGGHI SHYLLEKSRI CSPLGEERSY HIFYMLMAGG
PEGLRQKLGL TKPDDYNYLK NGCTRYFAKP ATEKILSPGQ KSAAQLKQGS LKDILIDDLE
DFKELDLALS RLGMSEVERL QIYTTVAAVL HLGNVEFEDN PEDTRGGCRV ARSGEKALIT
ASKLLEIDPE ELRQALVSRV MQSARGGLKG TVIMVPLKIH EANNARDALA KAIYSNLFDY
IVSRINQSIP FQASSYYIGV LDIAGFEFFT VNSFEQFCIN YCNEKLQQFF NERILKFEQE
LYKREGLSVP EISFTDNQDC IDVIEGKTQG IFALLDEESK LPKPSYAHFT ESVHKTWGKN
YRLGLPRSSK LKAHRSIRDD EGFLIKHFAG AVCYQTKQFI DKNNDALHAS LEGIIQDSKN
KLIQTLFATS MAQKGKLTFV SVGSKFKSQL QELLEKLRNN GTNFIRCIKP NNKMVDHQFD
GSLCLMQLTC SGMASVLELM EHGFPSRTPF ADLYNMYKEY LPNDLKKLSP RTFSEANTSI
QAHLKLTDKD FKFAITRVFF RPGKFAEFDK IMRSDPENLK SIVSNVKKWL VKSRWLKAQF
CALTVIKMKN KIVYRRKALV VIQKNVRGYL VKKKYGMRIK TVKNLRLMDG KLKQLDAIAQ
QLKSDKTSSI NGINQLKLEV NAAIGNIKKN ENIDNKTVEN LYSNLVLKID QQMSTLQKKV
QEQKSREEQE RLRKIQEEME KEKRIKEENE RRVREEEENR KKKAEMEAKR KLEEEARLRQ
ERDIYNLQKV TQEATDKKIA LELQQQQAKL EQEERLYQEQ LEQERQDREL ALRLAQETNG
QIEESPPLAR KSQPSNQVKG KHDLSKWKYS ELRDTINTSC DIELLEACRH EFHRRLKVYH
AWKAKNKKRT VMSENERAPL SVLESAQKTP RLPQKAILDN NSQRFFRIPF QRPGGDPNKR
GWWYAHFDGQ YVARQMELHP DKQPILLVAG QDDMQMCELS LEETGLTRKR GAEILENEFN
KEWEKNGGKT YIRPADRK
//
