ID N6X624_9ACTO Unreviewed; 555 AA.
AC N6X624;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Anaerobic glycerol-3-phosphate dehydrogenase {ECO:0000313|EMBL:ENO19136.1};
DE EC=1.1.5.3 {ECO:0000313|EMBL:ENO19136.1};
GN Name=glpA {ECO:0000313|EMBL:ENO19136.1};
GN ORFNames=HMPREF9004_0055 {ECO:0000313|EMBL:ENO19136.1};
OS Schaalia cardiffensis F0333.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Schaalia.
OX NCBI_TaxID=888050 {ECO:0000313|EMBL:ENO19136.1, ECO:0000313|Proteomes:UP000013015};
RN [1] {ECO:0000313|EMBL:ENO19136.1, ECO:0000313|Proteomes:UP000013015}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0333 {ECO:0000313|EMBL:ENO19136.1,
RC ECO:0000313|Proteomes:UP000013015};
RA Aqrawi P., Ayvaz T., Bess C., Blankenburg K., Coyle M., Deng J., Forbes L.,
RA Fowler G., Francisco L., Fu Q., Gibbs R., Gross S., Gubbala S., Hale W.,
RA Hemphill L., Highlander S., Hirani K., Jackson L., Jakkamsetti A.,
RA Javaid M., Jayaseelan J.C., Jiang H., Joshi V., Korchina V., Kovar C.,
RA Lara F., Lee S., Liu Y., Mata R., Mathew T., Munidasa M., Muzny D.,
RA Nazareth L., Ngo R., Nguyen L., Nguyen N., Okwuonu G., Ongeri F.,
RA Palculict T., Patil S., Petrosino J., Pham C., Pham P., Pu L.-L., Qin X.,
RA Qu J., Reid J., Ross M., Ruth R., Saada N., San Lucas F., Santibanez J.,
RA Shang Y., Simmons D., Song X.-Z., Tang L.-Y., Thornton R., Warren J.,
RA Weissenberger G., Wilczek-Boney K., Worley K., Youmans B., Zhang J.,
RA Zhang L., Zhao Z., Zhou C., Zhu D., Zhu Y.;
RT "Reference genome for the Human Microbiome Project.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the FAD-dependent glycerol-3-phosphate
CC dehydrogenase family. {ECO:0000256|ARBA:ARBA00007330}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENO19136.1}.
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DR EMBL; AQHZ01000001; ENO19136.1; -; Genomic_DNA.
DR AlphaFoldDB; N6X624; -.
DR STRING; 888050.HMPREF9004_0055; -.
DR PATRIC; fig|888050.3.peg.53; -.
DR eggNOG; COG0578; Bacteria.
DR HOGENOM; CLU_015740_0_1_11; -.
DR UniPathway; UPA00618; UER00673.
DR Proteomes; UP000013015; Unassembled WGS sequence.
DR GO; GO:0009331; C:glycerol-3-phosphate dehydrogenase complex; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0004368; F:glycerol-3-phosphate dehydrogenase (quinone) activity; IEA:UniProtKB-EC.
DR GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:InterPro.
DR CDD; cd19946; GlpA-like_Fer2_BFD-like; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR000447; G3P_DH_FAD-dep.
DR InterPro; IPR017752; G3P_DH_GlpA_su.
DR NCBIfam; TIGR03377; glycerol3P_GlpA; 1.
DR PANTHER; PTHR11985:SF36; ANAEROBIC GLYCEROL-3-PHOSPHATE DEHYDROGENASE SUBUNIT A; 1.
DR PANTHER; PTHR11985; GLYCEROL-3-PHOSPHATE DEHYDROGENASE; 1.
DR Pfam; PF01266; DAO; 1.
DR PRINTS; PR01001; FADG3PDH.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00978; FAD_G3PDH_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:ENO19136.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000013015}.
FT DOMAIN 8..358
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
SQ SEQUENCE 555 AA; 61133 MW; 380C2EF4DEC3CE7A CRC64;
MVKTINMDVV VIGGGSTGAG VVRDVAMRGF RTVLVERYDI AQGTSGRFHG LLHSGGRYIA
SDPESATECA EENEILKRIN SNAIEATGGL FVVTSQDDEE YADKFLERAA ATKVPAQEIS
LKEAFKREPR LDPGLKRAFE VLDGAVDGWQ MSWGAIRSAQ AYGAEIYTYH RVEKIEREGD
RISAVIVHNL RTGEDLRIEC SFVLNCGGPW AGQIAALAEC HGVDVVPGAG IMIAMNYRLT
QTVLNRCIWP ADGDILVPDH PVCIIGTTDL KAEDPDKLSI PADQVQQMLE SGEAMVPGFR
KARPLHAWAG ARPLVKDSRV AASDTRHMAR GMSVIDHHSR DGVSGMLTIA GGKLTTYRLM
AERIVNIMCE EMGEKRECRT AFEAVPPAVE QKLYTIGHRL EEIEHKNVAP SHDQIICECE
LITRTKLEEV MDTLPGAQLD DVRRQVRLGM GPCQGGFCSQ RATGIAHERG DIDSLKANEL
FRNFLKNRWI GLWPILYGKQ LRQTALDNWI HEGMLDVEHL PASATPSPEF VSFGQDITAA
RGAQATTDSE KEDHR
//
