ID N6XGI3_9RHOO Unreviewed; 432 AA.
AC N6XGI3;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=RND family efflux transporter MFP subunit {ECO:0000313|EMBL:ENO78510.1};
GN ORFNames=B447_14369 {ECO:0000313|EMBL:ENO78510.1};
OS Thauera sp. 27.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC Thauera.
OX NCBI_TaxID=305700 {ECO:0000313|EMBL:ENO78510.1, ECO:0000313|Proteomes:UP000013140};
RN [1] {ECO:0000313|EMBL:ENO78510.1, ECO:0000313|Proteomes:UP000013140}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=27 {ECO:0000313|EMBL:ENO78510.1,
RC ECO:0000313|Proteomes:UP000013140};
RA Liu B., Shapleigh J.P., Frostegard A.H.;
RT "Draft Genome Sequences of 6 Strains from Genus Thauera.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENO78510.1}.
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DR EMBL; AMXB01000026; ENO78510.1; -; Genomic_DNA.
DR RefSeq; WP_002929656.1; NZ_AMXB01000026.1.
DR AlphaFoldDB; N6XGI3; -.
DR eggNOG; COG0845; Bacteria.
DR Proteomes; UP000013140; Unassembled WGS sequence.
DR GO; GO:0019898; C:extrinsic component of membrane; IEA:InterPro.
DR GO; GO:1990195; C:macrolide transmembrane transporter complex; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 6.10.140.1990; -; 1.
DR Gene3D; 6.20.50.140; -; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR030190; MacA_alpha-hairpin_sf.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF33; EFFLUX PROTEIN; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000013140}.
FT DOMAIN 61..307
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 332..378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 111..193
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 332..349
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 432 AA; 46278 MW; 2D155E2834FC7317 CRC64;
MQNSNALPKP RTTGRRTVLA ALTISAALVV GAWLAWPKLF GERDPLAQYQ LATVQRGTVE
DVVTATGTLQ PRDYVDVGAQ VSGQLERIHV EVGSEVKEGD LLAQIDPTVY LARVDASRAQ
LRNLRAQLKD REAQLALAHI QLRRQRALMA EDASTQENLQ TAEASAKSAE AQLEALRAQI
EQIESTLRAD EANLQYARIL SPMAGTVVSI TARQGQTLNT NQQAPVVMRI ADLSTMTVQT
QVSEADISRL KLGMEAYFTT LGGAGKRWYG RLEKIEPTPT VTNNVVLYNA LFDVPNPDGK
LMTQMTAQVF FVVAQAKDAL LIPMAALSQG AVRTPQPGSA STSTAPGATP GNARADGQGR
RPGGRDSASM AGTRTLRVVG ERGTLEERSV EIGVTNRVQA QVLSGVREGE RVVSGIVSGA
AAGNRPPMTP RL
//
