ID N6XNG3_9RHOO Unreviewed; 357 AA.
AC N6XNG3;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN ORFNames=B447_10453 {ECO:0000313|EMBL:ENO80880.1};
OS Thauera sp. 27.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC Thauera.
OX NCBI_TaxID=305700 {ECO:0000313|EMBL:ENO80880.1, ECO:0000313|Proteomes:UP000013140};
RN [1] {ECO:0000313|EMBL:ENO80880.1, ECO:0000313|Proteomes:UP000013140}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=27 {ECO:0000313|EMBL:ENO80880.1,
RC ECO:0000313|Proteomes:UP000013140};
RA Liu B., Shapleigh J.P., Frostegard A.H.;
RT "Draft Genome Sequences of 6 Strains from Genus Thauera.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENO80880.1}.
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DR EMBL; AMXB01000016; ENO80880.1; -; Genomic_DNA.
DR RefSeq; WP_002939553.1; NZ_AMXB01000016.1.
DR AlphaFoldDB; N6XNG3; -.
DR eggNOG; COG0470; Bacteria.
DR Proteomes; UP000013140; Unassembled WGS sequence.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004622; DNA_pol_HolB.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00678; holB; 1.
DR PANTHER; PTHR11669:SF8; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR Pfam; PF13177; DNA_pol3_delta2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000013140};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REGION 85..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 357 AA; 38305 MW; 7A769EBA82236C7D CRC64;
MIHSWLQPTW TRLVELGDRL PHALLLVGPP GLGKRELADA LAARLLCDSP ADDGHACGRC
EPCVWRLADN HPDLHRVVPA AAAEAAAAER GEGEGGDAAG GREGGGKAAS AQIVIEQIRD
LQAALSVTGH HGARRVVVLD PAEAMNPFTA NALLKLLEEP PAGCVFLLVS SASRRLLPTI
RSRCQQWLFA RPEEHALAHW KTRTDPDVLA LLALGGGMPL AAERLARAGG GALLARFVRD
LAGLQASDAL KLAAQWESWL KSREALAAGF GLPELCDWMQ RWVSDLASVR LGGRVRFFPA
QQAVLSTLAS RCSVAAASAC YNEMAQIRRV SRHPLSLRLV LEDLLMRYVR ATAGVRG
//
