ID   N6XPX7_9RHOO            Unreviewed;      1031 AA.
AC   N6XPX7;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   SubName: Full=RND efflux transporter, permease protein {ECO:0000313|EMBL:ENO81400.1};
GN   ORFNames=B447_08603 {ECO:0000313|EMBL:ENO81400.1};
OS   Thauera sp. 27.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC   Thauera.
OX   NCBI_TaxID=305700 {ECO:0000313|EMBL:ENO81400.1, ECO:0000313|Proteomes:UP000013140};
RN   [1] {ECO:0000313|EMBL:ENO81400.1, ECO:0000313|Proteomes:UP000013140}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=27 {ECO:0000313|EMBL:ENO81400.1,
RC   ECO:0000313|Proteomes:UP000013140};
RA   Liu B., Shapleigh J.P., Frostegard A.H.;
RT   "Draft Genome Sequences of 6 Strains from Genus Thauera.";
RL   Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ENO81400.1}.
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DR   EMBL; AMXB01000012; ENO81400.1; -; Genomic_DNA.
DR   AlphaFoldDB; N6XPX7; -.
DR   eggNOG; COG0841; Bacteria.
DR   Proteomes; UP000013140; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF34; MULTIDRUG RESISTANCE PROTEIN MDTC; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000013140};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        335..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        361..382
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        429..452
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        464..486
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        529..549
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        858..875
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        908..933
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        953..974
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        986..1012
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1031 AA;  109671 MW;  56A96495199A7919 CRC64;
     MRALARLFVR RPVAASLLAL AWLLCGALAL RLMPVAPLPQ VDMPVIEVSA ALPGGSPETM
     ARMVSAPLER ALGSVAGVAE MSASTSQGAA RVRLTFEFDR DIDDAARDVQ AAINAAIGDL
     PAGMPGAPVY RKVNSAQAPI MVLALSSANL APGRLYDLAS TILAQKIAQM PGVGEVTVGG
     SALPAVRVQL DPASLESHGI ALDEVRRAIG DADAQLPLGA IEDGGLRWQV GAGPDLRVAA
     DFEQLVLRHD HGAMLRLGDV ARVSDGVENR YASGHHNRDP AVLLTVGRQP GANIVATIDT
     IRSQMPTLTA LLPADTTLDV VVDRSPGIRA SLDEAWATLW IAGTLVVLVV WAFLGSLRAA
     LIPALAVPVS LVGACALMYL AGFSLNNLSL MALIVAAGLV VDDAIVVLEN IERHIAAGMR
     PYRAAIVGLG EVGFTLLAMN LALIAVFASI LFMGGVIERL FREFSLTLVM AMTVSLMVSL
     TLAPALSGQM LLRPSEHPPS LLGRLASLVF GRLEAVYART LDWVLAHTWV VLLVLAVAVG
     LTVWLYLLVP KTMLPEQDTG QLRGLVRGDD GFSFQVMQPK IERFREYLLA DPAVADVVVT
     SGGSGGGMSN GWLMVRLKPL ALRGESARAA LERIRRNAPR EPGAILLLNI DQDLQLSAPF
     GGRGEELLLL GDDLARLTQW MRKVADGMRT LPEVADVDDF GNDATQIVVI DIDREAAARL
     GVDAELVTSL MNNAFSQRQV ATLFGRLNQY RVVMELEPGH TVDASVLDRL QVVTRDGQRV
     PLSAFVSYRY ELSSDRVFRA DQFAVVGVEY DLAPGVTASE AQQAINGLLA GLMLPNDIIA
     KPGGDGSRLQ QTMQAQPWLI LWVVVAVYVV LGVLYESTLH PLTILSTLPP AGVGALAALH
     LAGIEFSLIA LLGLFLLIGV VMKNAILMID FALDGERRLG LEPRSSIRRA ASLRLRPILM
     TNLAAVLAAL PLAFGVGEGA ELRRPLGIAI VGGLAVSQLL TLYTTPVVYL VLDRMRTGFT
     TARGGPAAAM R
//