GenomeNet

Database: UniProt
Entry: N8QBS8_9GAMM
LinkDB: N8QBS8_9GAMM
Original site: N8QBS8_9GAMM 
ID   N8QBS8_9GAMM            Unreviewed;       370 AA.
AC   N8QBS8;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   16-OCT-2019, entry version 31.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=F994_02856 {ECO:0000313|EMBL:ENU18729.1};
OS   Acinetobacter bohemicus ANC 3994.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Moraxellaceae; Acinetobacter.
OX   NCBI_TaxID=1217715 {ECO:0000313|EMBL:ENU18729.1, ECO:0000313|Proteomes:UP000013086};
RN   [1] {ECO:0000313|EMBL:ENU18729.1, ECO:0000313|Proteomes:UP000013086}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ANC 3994 {ECO:0000313|EMBL:ENU18729.1,
RC   ECO:0000313|Proteomes:UP000013086};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Cerqueira G., Feldgarden M., Courvalin P., Perichon B.,
RA   Grillot-Courvalin C., Clermont D., Rocha E., Yoon E.-J., Nemec A.,
RA   Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B.,
RA   Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA   Imamovic A., Larimer J., McCowan C., Murphy C., Neiman D., Pearson M.,
RA   Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Acinetobacter sp. ANC 3994.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ENU18729.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; APOH01000021; ENU18729.1; -; Genomic_DNA.
DR   RefSeq; WP_004649472.1; NZ_KB849166.1.
DR   STRING; 1217715.F994_02856; -.
DR   EnsemblBacteria; ENU18729; ENU18729; F994_02856.
DR   GeneID; 34390828; -.
DR   PATRIC; fig|1217715.3.peg.2792; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000013086; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000013086};
KW   Reference proteome {ECO:0000313|Proteomes:UP000013086};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       60    355       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   370 AA;  40668 MW;  CD96FFDC14E64B84 CRC64;
     MIKPVTAMNT LQSNPITQSD IDDVNVQSIQ PLVTPAELKK ELPLTEHAYQ TVLKGRETIR
     NILDGKDNRL FVVIGPCSIH DTVAAHEYAD RLKVLSEKIK DTLYIVMRVY FEKPRTTVGW
     KGLINDPDMN DSFNIEKGLR IGRQLLVELN NKGLPCATEA LDPNSPQYYQ DLISWSAIGA
     RTTESQTHRE MSSGLSSPVG FKNGTDGGLT VATNAMQSVK HGHSFLGLND QGQVSVIRTS
     GNPYAHVVLR GGNGKPNYDA GSVAEAENAL AKAKVSNKIM IDTSHANSNK DPYLQPLVLK
     NITEQILDGN KSIVGLMIES HLKGGRQDIP ENLDDLEYGQ SVTDGCIDWE TTEKALLDMH
     EALKDVLPNR
//
DBGET integrated database retrieval system