ID N9BUW7_9GAMM Unreviewed; 353 AA.
AC N9BUW7;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=F950_02417 {ECO:0000313|EMBL:ENV59863.1};
OS Acinetobacter soli NIPH 2899.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=1217677 {ECO:0000313|EMBL:ENV59863.1, ECO:0000313|Proteomes:UP000018433};
RN [1] {ECO:0000313|EMBL:ENV59863.1, ECO:0000313|Proteomes:UP000018433}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIPH 2899 {ECO:0000313|EMBL:ENV59863.1,
RC ECO:0000313|Proteomes:UP000018433};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Cerqueira G., Feldgarden M., Courvalin P., Perichon B.,
RA Grillot-Courvalin C., Clermont D., Rocha E., Yoon E.-J., Nemec A.,
RA Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B.,
RA Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., McCowan C., Murphy C., Neiman D., Pearson M.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Acinetobacter soli NIPH 2899.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENV59863.1}.
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DR EMBL; APPV01000011; ENV59863.1; -; Genomic_DNA.
DR RefSeq; WP_004947288.1; NZ_KB849643.1.
DR AlphaFoldDB; N9BUW7; -.
DR PATRIC; fig|1217677.3.peg.2359; -.
DR HOGENOM; CLU_009834_22_1_6; -.
DR Proteomes; UP000018433; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 16..331
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 353 AA; 40034 MW; 3052C70A6B9A03CF CRC64;
MNDHDDLEIR SEGALGIISL NRSSHLNALT LEMIRGIQAQ LDQWREDSQV QAVLIKSNAA
KAFCAGGDIR YLYDSYQAGN TQYQDFFATE YTMLSTIRNY SKPVIVMMDG YVLGGGFGLA
QACHIKITSE KSRFAMPETA IGFFPDVGAT YFLSRLDEVG VYMALTGAQI SSSDALYLDL
VDYHVPSEHF VALEHALSVA PILNPVEIRT IISSFITHPQ ESELQQHIDL INQYFSYPDI
SEIEQGLADA NDTLHQDWIK KMQAILEQRP EMAKQISLKL QQVGQNLSLE KCMQLERGLQ
DIWLQQGDFI EGVRALIVDK DKNPKWQTDN TEFKKTLEKF WPVWSKQHKD SLC
//
