ID N9WE39_9CLOT Unreviewed; 235 AA.
AC N9WE39;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Crp/Fnr family transcriptional regulator {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF1092_02014 {ECO:0000313|EMBL:ENZ01306.1};
OS Clostridium thermobutyricum.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=29372 {ECO:0000313|EMBL:ENZ01306.1, ECO:0000313|Proteomes:UP000013097};
RN [1] {ECO:0000313|EMBL:ENZ01306.1, ECO:0000313|Proteomes:UP000013097}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=209318 {ECO:0000313|EMBL:ENZ01306.1,
RC ECO:0000313|Proteomes:UP000013097};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Courvalin P., Lambert T.,
RA Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B.,
RA Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., McCowan C., Murphy C., Neiman D., Pearson M.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Clostridium colicanis 209318.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENZ01306.1}.
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DR EMBL; AGYT01000009; ENZ01306.1; -; Genomic_DNA.
DR RefSeq; WP_002598508.1; NZ_KB850956.1.
DR AlphaFoldDB; N9WE39; -.
DR PATRIC; fig|999411.4.peg.1982; -.
DR eggNOG; COG0664; Bacteria.
DR HOGENOM; CLU_075053_3_2_9; -.
DR Proteomes; UP000013097; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR CDD; cd00092; HTH_CRP; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR012318; HTH_CRP.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR24567; CRP FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR PANTHER; PTHR24567:SF78; LISTERIOLYSIN REGULATORY PROTEIN; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF13545; HTH_Crp_2; 1.
DR PRINTS; PR00034; HTHCRP.
DR SMART; SM00100; cNMP; 1.
DR SMART; SM00419; HTH_CRP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
DR PROSITE; PS51063; HTH_CRP_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000013097}.
FT DOMAIN 21..142
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 156..229
FT /note="HTH crp-type"
FT /evidence="ECO:0000259|PROSITE:PS51063"
SQ SEQUENCE 235 AA; 26557 MW; 9F326AF790BD1020 CRC64;
MKINACCDRC EKRLYAQEIP IFTSLSRNEL EQIIDLREHG HFKKGDVLFS EGDEISKLFI
VSNGLVKLTK NTFDGKEQII DILGVGDFFG ENNIIGDSHA MNVSAIAIQD LEVCTISRGD
LEKIITKNPQ IALKLLDGLN KKLKDVQNLS TNLASNVPES RIANILLKFA SDYSYDNNSE
ILINLPLNRE DIANYCGIAR ETLSRKLSYL EKLDIIEVHS KKIKIKDIEY LKELV
//
