ID   N9Y463_9CLOT            Unreviewed;       640 AA.
AC   N9Y463;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   RecName: Full=PrkA AAA domain-containing protein {ECO:0000259|SMART:SM00763};
GN   ORFNames=HMPREF1092_01842 {ECO:0000313|EMBL:ENZ02607.1};
OS   Clostridium thermobutyricum.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=29372 {ECO:0000313|EMBL:ENZ02607.1, ECO:0000313|Proteomes:UP000013097};
RN   [1] {ECO:0000313|EMBL:ENZ02607.1, ECO:0000313|Proteomes:UP000013097}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=209318 {ECO:0000313|EMBL:ENZ02607.1,
RC   ECO:0000313|Proteomes:UP000013097};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Courvalin P., Lambert T.,
RA   Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B.,
RA   Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA   Imamovic A., Larimer J., McCowan C., Murphy C., Neiman D., Pearson M.,
RA   Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Clostridium colicanis 209318.";
RL   Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ENZ02607.1}.
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DR   EMBL; AGYT01000008; ENZ02607.1; -; Genomic_DNA.
DR   RefSeq; WP_002598343.1; NZ_KB850956.1.
DR   AlphaFoldDB; N9Y463; -.
DR   PATRIC; fig|999411.4.peg.1814; -.
DR   eggNOG; COG2766; Bacteria.
DR   HOGENOM; CLU_028588_2_0_9; -.
DR   Proteomes; UP000013097; Unassembled WGS sequence.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013153; Prk_AAA_dom.
DR   InterPro; IPR010650; PrkA_C_dom.
DR   InterPro; IPR016230; Ser_kinase_PrkA.
DR   PANTHER; PTHR30267; PROTEIN KINASE PRKA; 1.
DR   PANTHER; PTHR30267:SF2; PROTEIN PRKA; 1.
DR   Pfam; PF08298; AAA_PrkA; 1.
DR   Pfam; PF06798; PrkA; 1.
DR   PIRSF; PIRSF000549; Ser_prot_kin; 1.
DR   SMART; SM00763; AAA_PrkA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000013097}.
FT   DOMAIN          21..378
FT                   /note="PrkA AAA"
FT                   /evidence="ECO:0000259|SMART:SM00763"
SQ   SEQUENCE   640 AA;  73389 MW;  5301036F31CC32BC CRC64;
     MDFREFIQTD RENREKEKFN GTFLDYLEIV KNNPDIVKLS HKRLYDKISE QGVEVLKGEE
     NYKIKRIYGN EIIRKYGFFK DNFFGIDKVI MKLMNYFHSA AMQGEEARQV LYLVGPVGAG
     KSSLVESLKK ALESCEQIYS IKGCPMHEEP LHLIPKHLRP DFEKMLGVKI EGDLCPVCKY
     RLINEYGGKY EEMPIEKKGF SIRSRKGIGV VPPVDPNNQD TSILTGSIDI SKMDMYAEDD
     PRIFSLNGAF NVGNRGMVEF IEVFKNDVEY LHTIITATQE KSIPSPGKGS MIYFDGVIVA
     HSNEAEWNKF KSDHTNEAIL DRIVKIEVPY CLELDEEIKI YEKILKKSNF NAHIAPHTIE
     IAAMFAILTR LMSSNKVDPI TKLKIYNGEE IVEKGSTKRI DIGELREEAG AYEGMKGIST
     RFIVKAIDNA LSNSEHNCIN PLSIMESIIK SVKEMDISSD DKKKYLGFIQ DTIRKEYNKI
     LEKEITKAFI HSFREQAESL FNNYIDNAEA FVNKSKIKDS STGEELNPDE EFMRSIEEYI
     GVSESSSKGF RADVTSYMFY LVRNGANIDY TSYEPLKEAI EKKLMASVKD LSRIITKSRV
     RNKEQKEKYN AMVAEMQNNG YCLHCCDVIL KYASNNLWKD
//