ID NFYC1_ARATH Reviewed; 234 AA.
AC Q9SMP0; O23635;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 27-MAR-2024, entry version 145.
DE RecName: Full=Nuclear transcription factor Y subunit C-1;
DE Short=AtNF-YC-1;
DE AltName: Full=Transcriptional activator HAP5A;
GN Name=NFYC1; Synonyms=HAP5A; OrderedLocusNames=At3g48590;
GN ORFNames=T8P19.100;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 80-155, AND TISSUE SPECIFICITY.
RX PubMed=9662544; DOI=10.1104/pp.117.3.1015;
RA Edwards D., Murray J.A.H., Smith A.G.;
RT "Multiple genes encoding the conserved CCAAT-box transcription factor
RT complex are expressed in Arabidopsis.";
RL Plant Physiol. 117:1015-1022(1998).
RN [6]
RP TISSUE SPECIFICITY.
RX PubMed=11250072; DOI=10.1016/s0378-1119(01)00323-7;
RA Gusmaroli G., Tonelli C., Mantovani R.;
RT "Regulation of the CCAAT-binding NF-Y subunits in Arabidopsis thaliana.";
RL Gene 264:173-185(2001).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11867211; DOI=10.1016/s0378-1119(01)00833-2;
RA Gusmaroli G., Tonelli C., Mantovani R.;
RT "Regulation of novel members of the Arabidopsis thaliana CCAAT-binding
RT nuclear factor Y subunits.";
RL Gene 283:41-48(2002).
RN [8]
RP TISSUE SPECIFICITY.
RC STRAIN=cv. Columbia, and cv. Wassilewskija;
RX PubMed=17322342; DOI=10.1104/pp.106.089904;
RA Warpeha K.M., Upadhyay S., Yeh J., Adamiak J., Hawkins S.I., Lapik Y.R.,
RA Anderson M.B., Kaufman L.S.;
RT "The GCR1, GPA1, PRN1, NF-Y signal chain mediates both blue light and
RT abscisic acid responses in Arabidopsis.";
RL Plant Physiol. 143:1590-1600(2007).
CC -!- FUNCTION: Stimulates the transcription of various genes by recognizing
CC and binding to a CCAAT motif in promoters. {ECO:0000250}.
CC -!- SUBUNIT: Heterotrimeric transcription factor composed of three
CC components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and
CC dimerize for NF-YA association and DNA binding (By similarity).
CC {ECO:0000250}.
CC -!- INTERACTION:
CC Q9SMP0; A0A178U8Q1: AXX17_At5g59430; NbExp=3; IntAct=EBI-2125944, EBI-15192959;
CC Q9SMP0; Q39057: CO; NbExp=8; IntAct=EBI-2125944, EBI-1639724;
CC Q9SMP0; Q944I5: NF-YB12; NbExp=3; IntAct=EBI-2125944, EBI-15192513;
CC Q9SMP0; Q945M9: NFYA9; NbExp=3; IntAct=EBI-2125944, EBI-15191941;
CC Q9SMP0; Q9SIT9: NFYB7; NbExp=3; IntAct=EBI-2125944, EBI-4459822;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Ubiquitous. Present in etiolated seedlings.
CC {ECO:0000269|PubMed:11250072, ECO:0000269|PubMed:17322342,
CC ECO:0000269|PubMed:9662544}.
CC -!- SIMILARITY: Belongs to the NFYC/HAP5 subunit family. {ECO:0000305}.
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DR EMBL; AL133315; CAB62348.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE78434.1; -; Genomic_DNA.
DR EMBL; AY092997; AAM12996.1; -; mRNA.
DR EMBL; BT001206; AAN65093.1; -; mRNA.
DR EMBL; AY086120; AAM63326.1; -; mRNA.
DR EMBL; Y13726; CAA74054.1; -; mRNA.
DR PIR; T46203; T46203.
DR RefSeq; NP_190428.1; NM_114718.4.
DR AlphaFoldDB; Q9SMP0; -.
DR SMR; Q9SMP0; -.
DR BioGRID; 9337; 50.
DR IntAct; Q9SMP0; 39.
DR STRING; 3702.Q9SMP0; -.
DR PaxDb; 3702-AT3G48590-1; -.
DR EnsemblPlants; AT3G48590.1; AT3G48590.1; AT3G48590.
DR GeneID; 824019; -.
DR Gramene; AT3G48590.1; AT3G48590.1; AT3G48590.
DR KEGG; ath:AT3G48590; -.
DR Araport; AT3G48590; -.
DR TAIR; AT3G48590; NF-YC1.
DR eggNOG; KOG1657; Eukaryota.
DR HOGENOM; CLU_045277_0_1_1; -.
DR InParanoid; Q9SMP0; -.
DR OMA; EDNSYAG; -.
DR OrthoDB; 940566at2759; -.
DR PhylomeDB; Q9SMP0; -.
DR PRO; PR:Q9SMP0; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9SMP0; baseline and differential.
DR Genevisible; Q9SMP0; AT.
DR GO; GO:0016602; C:CCAAT-binding factor complex; ISS:TAIR.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IDA:TAIR.
DR GO; GO:2000306; P:positive regulation of photomorphogenesis; IMP:TAIR.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; ISS:TAIR.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR007125; Histone_H2A/H2B/H3.
DR PANTHER; PTHR10252; HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED; 1.
DR PANTHER; PTHR10252:SF134; NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT C-1-RELATED; 1.
DR Pfam; PF00125; Histone; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
PE 1: Evidence at protein level;
KW Activator; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..234
FT /note="Nuclear transcription factor Y subunit C-1"
FT /id="PRO_0000218250"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 205..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 234 AA; 25329 MW; 65B0DD2F8FA14A44 CRC64;
MDTNNQQPPP SAAGIPPPPP GTTISAAGGG ASYHHLLQQQ QQQLQLFWTY QRQEIEQVND
FKNHQLPLAR IKKIMKADED VRMISAEAPI LFAKACELFI LELTIRSWLH AEENKRRTLQ
KNDIAAAITR TDIFDFLVDI VPRDEIKDEA AVLGGGMVVA PTASGVPYYY PPMGQPAGPG
GMMIGRPAMD PNGVYVQPPS QAWQSVWQTS TGTGDDVSYG SGGSSGQGNL DGQG
//
