ID NFYC2_ORYSJ Reviewed; 246 AA.
AC A6BLW4; Q10P13;
DT 05-OCT-2016, integrated into UniProtKB/Swiss-Prot.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE RecName: Full=Nuclear transcription factor Y subunit C-2 {ECO:0000305};
DE Short=OsNF-YC2 {ECO:0000303|PubMed:26542958};
DE AltName: Full=Transcriptional activator HAP5C {ECO:0000305};
DE Short=OsHAP5C {ECO:0000303|PubMed:18193457};
GN Name=NFYC2 {ECO:0000305}; Synonyms=HAP5C {ECO:0000303|PubMed:18193457};
GN OrderedLocusNames=Os03g0251350 {ECO:0000312|EMBL:BAH92080.1},
GN LOC_Os03g14669 {ECO:0000312|EMBL:ABF94991.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=18193457; DOI=10.1007/s00438-007-0312-3;
RA Thirumurugan T., Ito Y., Kubo T., Serizawa A., Kurata N.;
RT "Identification, characterization and interaction of HAP family genes in
RT rice.";
RL Mol. Genet. Genomics 279:279-289(2008).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG The rice chromosome 3 sequencing consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP FUNCTION, INTERACTION WITH NFYB8; NFYB10 AND HD5/NFYB11, SUBCELLULAR
RP LOCATION, AND INDUCTION.
RX PubMed=26542958; DOI=10.1007/s00425-015-2426-x;
RA Kim S.K., Park H.Y., Jang Y.H., Lee K.C., Chung Y.S., Lee J.H., Kim J.K.;
RT "OsNF-YC2 and OsNF-YC4 proteins inhibit flowering under long-day conditions
RT in rice.";
RL Planta 243:563-576(2016).
CC -!- FUNCTION: Probable transcription factor involved in the regulation of
CC flowering time under long day (LD) conditions. Functions as a repressor
CC of flowering, independently of HD1 and GHD7. Controls flowering time by
CC negatively regulating the expression of EHD1 and HD3A
CC (PubMed:26542958). Component of the NF-Y/HAP transcription factor
CC complex (By similarity). {ECO:0000250, ECO:0000269|PubMed:26542958}.
CC -!- SUBUNIT: Heterotrimeric transcription factor composed of three
CC components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and
CC dimerize for NF-YA association and DNA binding (By similarity).
CC Interacts with NFYB8, NFYB10 and HD5/NFYB11 (PubMed:26542958).
CC {ECO:0000250, ECO:0000269|PubMed:26542958}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:26542958}. Cytoplasm
CC {ECO:0000269|PubMed:26542958}.
CC -!- INDUCTION: Circadian-regulation under long day (LD) conditions.
CC Expression increases at the end of the dark period, peaks in the
CC beginning of the light period and gradually decreases during daytime.
CC {ECO:0000269|PubMed:26542958}.
CC -!- SIMILARITY: Belongs to the NFYC/HAP5 subunit family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABF94991.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB288043; BAF64451.1; -; Genomic_DNA.
DR EMBL; DP000009; ABF94991.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008209; BAH92080.1; -; Genomic_DNA.
DR EMBL; AP014959; BAS83288.1; -; Genomic_DNA.
DR RefSeq; XP_015628319.1; XM_015772833.1.
DR RefSeq; XP_015628320.1; XM_015772834.1.
DR PDB; 7C9O; X-ray; 2.55 A; C=55-156.
DR PDB; 7C9P; X-ray; 2.00 A; B/D=55-156.
DR PDBsum; 7C9O; -.
DR PDBsum; 7C9P; -.
DR AlphaFoldDB; A6BLW4; -.
DR SMR; A6BLW4; -.
DR STRING; 39947.A6BLW4; -.
DR PaxDb; 39947-A6BLW4; -.
DR EnsemblPlants; Os03t0251350-01; Os03t0251350-01; Os03g0251350.
DR GeneID; 9266204; -.
DR Gramene; Os03t0251350-01; Os03t0251350-01; Os03g0251350.
DR KEGG; osa:9266204; -.
DR eggNOG; KOG1657; Eukaryota.
DR HOGENOM; CLU_045277_0_1_1; -.
DR InParanoid; A6BLW4; -.
DR OMA; GMMTIGR; -.
DR OrthoDB; 940566at2759; -.
DR Proteomes; UP000000763; Chromosome 3.
DR Proteomes; UP000059680; Chromosome 3.
DR GO; GO:0005737; C:cytoplasm; IDA:UniProtKB.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR GO; GO:0048579; P:negative regulation of long-day photoperiodism, flowering; IMP:UniProtKB.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR007125; Histone_H2A/H2B/H3.
DR PANTHER; PTHR10252; HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED; 1.
DR PANTHER; PTHR10252:SF39; NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT C-6; 1.
DR Pfam; PF00125; Histone; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cytoplasm; DNA-binding; Flowering; Nucleus;
KW Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..246
FT /note="Nuclear transcription factor Y subunit C-2"
FT /id="PRO_0000437434"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 205..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT HELIX 72..80
FT /evidence="ECO:0007829|PDB:7C9P"
FT HELIX 91..117
FT /evidence="ECO:0007829|PDB:7C9P"
FT STRAND 121..123
FT /evidence="ECO:0007829|PDB:7C9P"
FT HELIX 125..133
FT /evidence="ECO:0007829|PDB:7C9P"
FT HELIX 136..141
FT /evidence="ECO:0007829|PDB:7C9P"
FT TURN 142..144
FT /evidence="ECO:0007829|PDB:7C9P"
SQ SEQUENCE 246 AA; 25896 MW; EDAA28E497713F3C CRC64;
MDNQQLPYAG QPAAAGAGAP VPGVPGAGGP PAVPHHHLLQ QQQAQLQAFW AYQRQEAERA
SASDFKNHQL PLARIKKIMK ADEDVRMISA EAPVLFAKAC ELFILELTIR SWLHAEENKR
RTLQRNDVAA AIARTDVFDF LVDIVPREEA KEEPGSALGF AAGGPAGAVG AAGPAAGLPY
YYPPMGQPAP MMPAWHVPAW DPAWQQGAAP DVDQGAAGSF SEEGQQGFAG HGGAAASFPP
APPSSE
//
