ID IMP3_SCHPO Reviewed; 183 AA.
AC O13835;
DT 27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 27-MAR-2024, entry version 127.
DE RecName: Full=U3 small nucleolar ribonucleoprotein protein imp3;
DE Short=U3 snoRNP protein imp3;
GN Name=imp3; ORFNames=SPAC19D5.05c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: Component of the U3 small nucleolar ribonucleoprotein.
CC Required for the early cleavages at sites A0, A1 and A2 during 18S
CC ribosomal pre-RNA processing (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Component of a heterotrimeric complex containing imp3, imp4
CC and mpp10. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS4 family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU329670; CAB16715.1; -; Genomic_DNA.
DR PIR; T37965; T37965.
DR RefSeq; NP_594903.1; NM_001020332.2.
DR AlphaFoldDB; O13835; -.
DR SMR; O13835; -.
DR BioGRID; 278972; 4.
DR STRING; 284812.O13835; -.
DR MaxQB; O13835; -.
DR PaxDb; 4896-SPAC19D5-05c-1; -.
DR EnsemblFungi; SPAC19D5.05c.1; SPAC19D5.05c.1:pep; SPAC19D5.05c.
DR GeneID; 2542514; -.
DR KEGG; spo:SPAC19D5.05c; -.
DR PomBase; SPAC19D5.05c; imp3.
DR VEuPathDB; FungiDB:SPAC19D5.05c; -.
DR eggNOG; KOG4655; Eukaryota.
DR HOGENOM; CLU_097281_0_0_1; -.
DR InParanoid; O13835; -.
DR OMA; FRIKHEQ; -.
DR PhylomeDB; O13835; -.
DR Reactome; R-SPO-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR PRO; PR:O13835; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0034457; C:Mpp10 complex; IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0030532; C:small nuclear ribonucleoprotein complex; ISO:PomBase.
DR GO; GO:0015935; C:small ribosomal subunit; IEA:InterPro.
DR GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR GO; GO:0005732; C:sno(s)RNA-containing ribonucleoprotein complex; ISO:PomBase.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030515; F:snoRNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0042274; P:ribosomal small subunit biogenesis; ISO:PomBase.
DR GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR CDD; cd00165; S4; 1.
DR Gene3D; 3.10.290.10; RNA-binding S4 domain; 1.
DR InterPro; IPR022801; Ribosomal_uS4.
DR InterPro; IPR001912; Ribosomal_uS4_N.
DR InterPro; IPR002942; S4_RNA-bd.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR PANTHER; PTHR11831; 30S 40S RIBOSOMAL PROTEIN; 1.
DR PANTHER; PTHR11831:SF1; U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP3; 1.
DR Pfam; PF00163; Ribosomal_S4; 1.
DR Pfam; PF01479; S4; 1.
DR SMART; SM01390; Ribosomal_S4; 1.
DR SMART; SM00363; S4; 1.
DR SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1.
DR PROSITE; PS50889; S4; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW RNA-binding; rRNA processing; rRNA-binding.
FT CHAIN 1..183
FT /note="U3 small nucleolar ribonucleoprotein protein imp3"
FT /id="PRO_0000132711"
FT DOMAIN 109..175
FT /note="S4 RNA-binding"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00182"
SQ SEQUENCE 183 AA; 21777 MW; 0841BA52BBC98ED8 CRC64;
MRILKHHEQK LLRKVDFLNY KNDDNNHRDV MVMRRYHISK REEYQKYNII CGKFRQLAHR
LSLLDPTDPF RLQYENLLLE KLFDMGILPS KSKMSDIENK ANVSAICRRR LPVIMCKLRM
SQVVSEATRL IEQGHVRVGP HVITDPAYLV TRSLEDFVTW TDTSKIKRTI AKYNDKLDDY
DLL
//
