ID O28233_ARCFU Unreviewed; 248 AA.
AC O28233;
DT 01-JAN-1998, integrated into UniProtKB/TrEMBL.
DT 01-JAN-1998, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=Cytochrome oxidase, subunit I, putative {ECO:0000313|EMBL:AAB89200.1};
GN OrderedLocusNames=AF_2046 {ECO:0000313|EMBL:AAB89200.1};
OS Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS 100126 / VC-16).
OC Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC Archaeoglobus.
OX NCBI_TaxID=224325 {ECO:0000313|EMBL:AAB89200.1, ECO:0000313|Proteomes:UP000002199};
RN [1] {ECO:0000313|EMBL:AAB89200.1, ECO:0000313|Proteomes:UP000002199}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16
RC {ECO:0000313|Proteomes:UP000002199};
RX PubMed=9389475; DOI=10.1038/37052;
RA Klenk H.P., Clayton R.A., Tomb J., White O., Nelson K.E., Ketchum K.A.,
RA Dodson R.J., Gwinn M., Hickey E.K., Peterson J.D., Richardson D.L.,
RA Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA Quackenbush J., Lee N.H., Sutton G.G., Gill S., Kirkness E.F.,
RA Dougherty B.A., McKenney K., Adams M.D., Loftus B., Peterson S.,
RA Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA Gocayne J.D., Weidman J.F., McDonald L., Utterback T., Cotton M.D.,
RA Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA Smith H.O., Woese C.R., Venter J.C.;
RT "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT archaeon Archaeoglobus fulgidus.";
RL Nature 390:364-370(1997).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AE000782; AAB89200.1; -; Genomic_DNA.
DR PIR; E69505; E69505.
DR RefSeq; WP_010879538.1; NC_000917.1.
DR AlphaFoldDB; O28233; -.
DR STRING; 224325.AF_2046; -.
DR PaxDb; 224325-AF_2046; -.
DR EnsemblBacteria; AAB89200; AAB89200; AF_2046.
DR GeneID; 1485273; -.
DR KEGG; afu:AF_2046; -.
DR eggNOG; arCOG04471; Archaea.
DR HOGENOM; CLU_065734_1_0_2; -.
DR OrthoDB; 200496at2157; -.
DR PhylomeDB; O28233; -.
DR Proteomes; UP000002199; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR InterPro; IPR014522; ArtA.
DR InterPro; IPR026392; Exo/Archaeosortase_dom.
DR InterPro; IPR019127; Exosortase.
DR NCBIfam; TIGR04178; exo_archaeo; 1.
DR NCBIfam; TIGR04125; exosort_PGF_TRM; 1.
DR Pfam; PF09721; Exosortase_EpsH; 1.
DR PIRSF; PIRSF025737; Cyco1; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000002199};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT ACT_SITE 143
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR025737-1"
FT ACT_SITE 184
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR025737-1"
SQ SEQUENCE 248 AA; 27107 MW; CF53E92F5114F5BE CRC64;
MLAEVISAVS LIPMLVYVKT RSNFAGFLGW ALFSAACLIK VPDYLSSADY YNTAVFFLAY
VFFLYMAIKI LTANSQTFVD VTAFSALAFV VYFPFAFTPL GDALIDCTAH LTASLANLLG
YGVVKEGVNL YLNGRSVRII LACTAIESMA LFTGATLGVR AEVSRKVKAF LISVPVIYVL
NLFRNVFVTV SFAYSWFGEN SFYIAHNVVS KIGSTLALIF IAYGVFKLLP ELADLIYSLK
DELVGGGR
//
