ID O29251_ARCFU Unreviewed; 330 AA.
AC O29251;
DT 01-JAN-1998, integrated into UniProtKB/TrEMBL.
DT 01-JAN-1998, sequence version 1.
DT 27-MAR-2024, entry version 121.
DE RecName: Full=AN1-type domain-containing protein {ECO:0000259|PROSITE:PS51039};
GN OrderedLocusNames=AF_1011 {ECO:0000313|EMBL:AAB90231.1};
OS Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS 100126 / VC-16).
OC Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC Archaeoglobus.
OX NCBI_TaxID=224325 {ECO:0000313|EMBL:AAB90231.1, ECO:0000313|Proteomes:UP000002199};
RN [1] {ECO:0000313|EMBL:AAB90231.1, ECO:0000313|Proteomes:UP000002199}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16
RC {ECO:0000313|Proteomes:UP000002199};
RX PubMed=9389475; DOI=10.1038/37052;
RA Klenk H.P., Clayton R.A., Tomb J., White O., Nelson K.E., Ketchum K.A.,
RA Dodson R.J., Gwinn M., Hickey E.K., Peterson J.D., Richardson D.L.,
RA Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA Quackenbush J., Lee N.H., Sutton G.G., Gill S., Kirkness E.F.,
RA Dougherty B.A., McKenney K., Adams M.D., Loftus B., Peterson S.,
RA Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA Gocayne J.D., Weidman J.F., McDonald L., Utterback T., Cotton M.D.,
RA Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA Smith H.O., Woese C.R., Venter J.C.;
RT "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT archaeon Archaeoglobus fulgidus.";
RL Nature 390:364-370(1997).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the peptidase S54 family.
CC {ECO:0000256|ARBA:ARBA00009045}.
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DR EMBL; AE000782; AAB90231.1; -; Genomic_DNA.
DR PIR; C69376; C69376.
DR AlphaFoldDB; O29251; -.
DR STRING; 224325.AF_1011; -.
DR BindingDB; O29251; -.
DR PaxDb; 224325-AF_1011; -.
DR EnsemblBacteria; AAB90231; AAB90231; AF_1011.
DR KEGG; afu:AF_1011; -.
DR eggNOG; arCOG01768; Archaea.
DR HOGENOM; CLU_055068_1_0_2; -.
DR PhylomeDB; O29251; -.
DR Proteomes; UP000002199; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 4.10.1110.10; AN1-like Zinc finger; 1.
DR Gene3D; 1.20.1540.10; Rhomboid-like; 1.
DR InterPro; IPR035896; AN1-like_Znf.
DR InterPro; IPR022764; Peptidase_S54_rhomboid_dom.
DR InterPro; IPR035952; Rhomboid-like_sf.
DR InterPro; IPR000058; Znf_AN1.
DR PANTHER; PTHR43731:SF26; RHOMBOID DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43731; RHOMBOID PROTEASE; 1.
DR Pfam; PF01694; Rhomboid; 1.
DR Pfam; PF01428; zf-AN1; 1.
DR SMART; SM00154; ZnF_AN1; 1.
DR SUPFAM; SSF118310; AN1-like Zinc finger; 1.
DR SUPFAM; SSF144091; Rhomboid-like; 1.
DR PROSITE; PS51039; ZF_AN1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002199};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT TRANSMEM 131..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 60..106
FT /note="AN1-type"
FT /evidence="ECO:0000259|PROSITE:PS51039"
SQ SEQUENCE 330 AA; 37464 MW; 4B0448870D1DB6DC CRC64;
MLLHSFSRFK LLRGFLSLAA ANYAMKHLPL FSTAVENFAL FPRLPNSTQA EAFLTSRSLM
LRVARCDVCG EEVTIPFKCK YCGGTFCAEH RLPENHDCDG LDEYWNVPVN VKRRLSPQPA
RRSRNIGLMK YGANNTVLII CTILFFISIV APYEMVEIFA LHPRLDVLLA MPWQLITSMF
LHVEFWHFFV NMFVLLFFGT ELERRLGDRK YLEIFFVSGL AGNVGYIAYS YAVGSFAPAL
GASAAIFGVM GCLAIIAPEI RIIIFPIPIP INIRTALLLF AAYDFWMMVA SYMGLFYTNV
ANIAHLAGLA VGLYYGKRLG RRKVRYDFYF
//
