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Database: UniProt
Entry: O30012_ARCFU
LinkDB: O30012_ARCFU
Original site: O30012_ARCFU 
ID   O30012_ARCFU            Unreviewed;       620 AA.
AC   O30012;
DT   01-JAN-1998, integrated into UniProtKB/TrEMBL.
DT   01-JAN-1998, sequence version 1.
DT   08-MAY-2019, entry version 106.
DE   SubName: Full=Chorismate mutase/prephenate dehydratase (PheA) {ECO:0000313|EMBL:AAB91005.1};
GN   OrderedLocusNames=AF_0227 {ECO:0000313|EMBL:AAB91005.1};
OS   Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM
OS   9628 / NBRC 100126).
OC   Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales;
OC   Archaeoglobaceae; Archaeoglobus.
OX   NCBI_TaxID=224325 {ECO:0000313|EMBL:AAB91005.1, ECO:0000313|Proteomes:UP000002199};
RN   [1] {ECO:0000313|EMBL:AAB91005.1, ECO:0000313|Proteomes:UP000002199}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126
RC   {ECO:0000313|Proteomes:UP000002199};
RX   PubMed=9389475; DOI=10.1038/37052;
RA   Klenk H.P., Clayton R.A., Tomb J., White O., Nelson K.E.,
RA   Ketchum K.A., Dodson R.J., Gwinn M., Hickey E.K., Peterson J.D.,
RA   Richardson D.L., Kerlavage A.R., Graham D.E., Kyrpides N.C.,
RA   Fleischmann R.D., Quackenbush J., Lee N.H., Sutton G.G., Gill S.,
RA   Kirkness E.F., Dougherty B.A., McKenney K., Adams M.D., Loftus B.,
RA   Peterson S., Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L.,
RA   Overbeek R., Gocayne J.D., Weidman J.F., McDonald L., Utterback T.,
RA   Cotton M.D., Spriggs T., Artiach P., Kaine B.P., Sykes S.M.,
RA   Sadow P.W., D'Andrea K.P., Bowman C., Fujii C., Garland S.A.,
RA   Mason T.M., Olsen G.J., Fraser C.M., Smith H.O., Woese C.R.,
RA   Venter J.C.;
RT   "The complete genome sequence of the hyperthermophilic, sulphate-
RT   reducing archaeon Archaeoglobus fulgidus.";
RL   Nature 390:364-370(1997).
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DR   EMBL; AE000782; AAB91005.1; -; Genomic_DNA.
DR   PIR; C69278; C69278.
DR   STRING; 224325.AF_0227; -.
DR   EnsemblBacteria; AAB91005; AAB91005; AF_0227.
DR   KEGG; afu:AF_0227; -.
DR   eggNOG; ENOG4102T9Y; Archaea.
DR   eggNOG; COG0077; LUCA.
DR   eggNOG; COG0287; LUCA.
DR   eggNOG; COG1605; LUCA.
DR   KO; K14170; -.
DR   OMA; CMGFINN; -.
DR   BRENDA; 1.3.1.12; 414.
DR   BRENDA; 4.2.1.51; 414.
DR   BRENDA; 5.4.99.5; 414.
DR   Proteomes; UP000002199; Chromosome.
DR   GO; GO:0004664; F:prephenate dehydratase activity; IEA:InterPro.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0046417; P:chorismate metabolic process; IEA:InterPro.
DR   GO; GO:0009094; P:L-phenylalanine biosynthetic process; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.20.59.10; -; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR036263; Chorismate_II_sf.
DR   InterPro; IPR010950; Chorismate_mutase_arc.
DR   InterPro; IPR036979; CM_dom_sf.
DR   InterPro; IPR002701; CM_II_prokaryot.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR001086; Preph_deHydtase.
DR   InterPro; IPR003099; Prephen_DH.
DR   Pfam; PF01842; ACT; 1.
DR   Pfam; PF01817; CM_2; 1.
DR   Pfam; PF02153; PDH; 1.
DR   Pfam; PF00800; PDT; 1.
DR   SMART; SM00830; CM_2; 1.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   SUPFAM; SSF48600; SSF48600; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   TIGRFAMs; TIGR01791; CM_archaeal; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS51168; CHORISMATE_MUT_2; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
DR   PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002199};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002199}.
FT   DOMAIN        4    262       Prephenate/arogenate dehydrogenase.
FT                                {ECO:0000259|PROSITE:PS51176}.
FT   DOMAIN      260    348       Chorismate mutase. {ECO:0000259|PROSITE:
FT                                PS51168}.
FT   DOMAIN      353    528       Prephenate dehydratase.
FT                                {ECO:0000259|PROSITE:PS51171}.
FT   DOMAIN      539    612       ACT. {ECO:0000259|PROSITE:PS51671}.
FT   COILED      206    226       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   620 AA;  70947 MW;  9D5C0FDEFA6B9A65 CRC64;
     MISVKILIYG VGNMGKLFRD IFYGKGYYVR GYDIDQMKRD TNSISGFDVI FVCTPMYALE
     EALEHIKREA KKEALLVDVS SVKKVSVPLF EESGFDFLSI HPMLGGDSEI SLSNVIVVRE
     SGREEEKVIL EELRKCGAVL SRLDVEEHDR KMAEIQGIAH FALVSMADFL RYGKEELKYA
     SPIFTVLYKL ASRIINQNWE MYFQIQKNAE DVREEYLRRA MELHEKMKDR ESFREIFESL
     RKIYTDYESS TIILESYKAT KKAESIEELR GLIKSIDSLI LRLIERRIDA ARQIARIKME
     RGEPIELKDV EEEKLWEVMS KTTLNPVKLK EIFEGIMSLA KEEEYKVAGV KYTIAVLGPQ
     GSFSEEMALK LVGSRVPLRY CSTTDEIIKL VESGEVDYGL VPIENSVNGT VLPVIDALLN
     HDVEVFGEAK LEVNHCLVAK RKIELKEIKT IYSHPQAVAQ CMGFINNYLP SVAIRYTTST
     SDAARMLDDY SAAIMSENAA RFYRLHVLRK GIQDLKGRNI TRFYLIRRRS GRSEGKITSL
     FFGVEDKPGA LKDVLEVFHK KGFNLRKLES RPAGTGLGDY VFFVEVEAPL REEDLLDLKQ
     VTTFYKVVGV FDEVKRMSTL
//
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