ID O44466_CAEEL Unreviewed; 226 AA.
AC O44466;
DT 01-JUN-1998, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1999, sequence version 2.
DT 27-MAR-2024, entry version 154.
DE SubName: Full=Thyroglobulin type-1 domain-containing protein {ECO:0000313|EMBL:CCD68035.1};
GN Name=test-1 {ECO:0000313|EMBL:CCD68035.1,
GN ECO:0000313|WormBase:C54E4.2a};
GN ORFNames=C54E4.2 {ECO:0000313|WormBase:C54E4.2a}, CELE_C54E4.2
GN {ECO:0000313|EMBL:CCD68035.1};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD68035.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CCD68035.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCD68035.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00500}.
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DR EMBL; BX284604; CCD68035.1; -; Genomic_DNA.
DR RefSeq; NP_001023098.1; NM_001027927.3.
DR AlphaFoldDB; O44466; -.
DR SMR; O44466; -.
DR EPD; O44466; -.
DR EnsemblMetazoa; C54E4.2a.1; C54E4.2a.1; WBGene00016918.
DR GeneID; 177010; -.
DR KEGG; cel:CELE_C54E4.2; -.
DR UCSC; C54E4.2b; c. elegans.
DR AGR; WB:WBGene00016918; -.
DR WormBase; C54E4.2a; CE20611; WBGene00016918; test-1.
DR InParanoid; O44466; -.
DR OrthoDB; 4174283at2759; -.
DR Proteomes; UP000001940; Chromosome IV.
DR Bgee; WBGene00016918; Expressed in larva and 4 other cell types or tissues.
DR ExpressionAtlas; O44466; baseline and differential.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd16232; EFh_SPARC_TICN; 1.
DR CDD; cd00191; TY; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 4.10.800.10; Thyroglobulin type-1; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR019577; SPARC/Testican_Ca-bd-dom.
DR InterPro; IPR000716; Thyroglobulin_1.
DR InterPro; IPR036857; Thyroglobulin_1_sf.
DR PANTHER; PTHR13866:SF27; KAZAL-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13866; SPARC OSTEONECTIN; 1.
DR Pfam; PF10591; SPARC_Ca_bdg; 1.
DR Pfam; PF00086; Thyroglobulin_1; 1.
DR SMART; SM00211; TY; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF57610; Thyroglobulin type-1 domain; 1.
DR PROSITE; PS00484; THYROGLOBULIN_1_1; 1.
DR PROSITE; PS51162; THYROGLOBULIN_1_2; 1.
PE 1: Evidence at protein level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00500};
KW Proteomics identification {ECO:0007829|EPD:O44466,
KW ECO:0007829|PeptideAtlas:O44466};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..226
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004158413"
FT DOMAIN 147..207
FT /note="Thyroglobulin type-1"
FT /evidence="ECO:0000259|PROSITE:PS51162"
FT DISULFID 150..169
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00500"
FT DISULFID 187..207
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00500"
SQ SEQUENCE 226 AA; 25806 MW; 4C8CE5C8F1002DA9 CRC64;
MRLIVAILAC HVAISAAYIS SEDLEKPSSA DKPVHEKNHC TRSELMRMGG RLVKWFKDVH
AQESGADHTL KLHSVPCRVE VGWMFNQWDG NQDGKLSKAE LRPIERGGNE ACVEEFIDMC
DDMVVDGSIS VDEWCDCFTF SDDLRHEPPC HKAKHDVDPH LLGVFLPRCD LEGFYKPEQC
HDGNCWCVDR YGREFDKSRV QNTLPDCGQY ASDMTEEDIA FLRERL
//
