ID O45173_CAEEL Unreviewed; 423 AA.
AC O45173;
DT 01-JUN-1998, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 3.
DT 27-MAR-2024, entry version 139.
DE SubName: Full=G-protein coupled receptors family 1 profile domain-containing protein {ECO:0000313|EMBL:CCD66732.2};
GN ORFNames=CELE_K03H6.1 {ECO:0000313|EMBL:CCD66732.2}, K03H6.1
GN {ECO:0000313|EMBL:CCD66732.2, ECO:0000313|WormBase:K03H6.1};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD66732.2, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CCD66732.2, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCD66732.2,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688}.
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DR EMBL; BX284604; CCD66732.2; -; Genomic_DNA.
DR RefSeq; NP_500092.3; NM_067691.3.
DR AlphaFoldDB; O45173; -.
DR SMR; O45173; -.
DR STRING; 6239.K03H6.1.1; -.
DR PaxDb; 6239-K03H6-1; -.
DR EnsemblMetazoa; K03H6.1.1; K03H6.1.1; WBGene00019367.
DR GeneID; 186962; -.
DR KEGG; cel:CELE_K03H6.1; -.
DR UCSC; K03H6.1; c. elegans.
DR AGR; WB:WBGene00019367; -.
DR WormBase; K03H6.1; CE48606; WBGene00019367; -.
DR eggNOG; ENOG502T7JC; Eukaryota.
DR HOGENOM; CLU_009579_24_3_1; -.
DR InParanoid; O45173; -.
DR OMA; AFDTIAY; -.
DR OrthoDB; 2874883at2759; -.
DR Proteomes; UP000001940; Chromosome IV.
DR Bgee; WBGene00019367; Expressed in larva and 2 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008528; F:G protein-coupled peptide receptor activity; IEA:InterPro.
DR CDD; cd14978; 7tmA_FMRFamide_R-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR019427; 7TM_GPCR_serpentine_rcpt_Srw.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR46895:SF6; G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46895; PROTEIN CBG20548-RELATED; 1.
DR Pfam; PF10324; 7TM_GPCR_Srw; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW G-protein coupled receptor {ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|RuleBase:RU000688, ECO:0000313|EMBL:CCD66732.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Transducer {ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 35..320
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 423 AA; 48570 MW; ED03C54396615BA2 CRC64;
MACLKKAQLL FFRDPLSRFI WQYVFPLQFA LGLLGNSLNL WVLASDEVPN IASDMLAAVS
FCDLAFLLVM LPNCLAAFDT IAYNVSFRYF YLNTKQHMSA VANWMSAAAI WLILAVSIER
YLIVRSPFRA KLYWQRGKMV VVLSSIFVTT GLLTVYHHFE WDCVIEEFCN GTQLLDFCYY
SGMRHQKTYR NKDWVTPSNV KKVYLKFSTF LNAILVVFVP IVLVIVLNML MIRQLKINWT
SPRLESMRGA MTRSHVRQRQ RVAVTVIAIG LCFSLTQGPS AFMALYELFS EYELGHTFYA
IFSITNSLVV TGKTINFILF CLSSEHFRQK CFKAIYRKFP KLSQSSIGKR FLDHQRSNSY
DRSSSLRTVR SRRGSATTLP GVNRDTLLLP PSEECATCSL SVSRQNISYR TRLHSEPSVS
SER
//
