ID O45353_CAEEL Unreviewed; 326 AA.
AC O45353;
DT 01-JUN-1998, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 2.
DT 27-MAR-2024, entry version 131.
DE SubName: Full=G-protein coupled receptors family 1 profile domain-containing protein {ECO:0000313|EMBL:CAB07575.2};
GN Name=srv-34 {ECO:0000313|EMBL:CAB07575.2,
GN ECO:0000313|WormBase:F13A7.3};
GN ORFNames=CELE_F13A7.3 {ECO:0000313|EMBL:CAB07575.2}, F13A7.3
GN {ECO:0000313|WormBase:F13A7.3};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CAB07575.2, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CAB07575.2, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAB07575.2,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; BX284605; CAB07575.2; -; Genomic_DNA.
DR PIR; T20809; T20809.
DR RefSeq; NP_507135.2; NM_074734.2.
DR AlphaFoldDB; O45353; -.
DR SMR; O45353; -.
DR PaxDb; 6239-F13A7-3; -.
DR EnsemblMetazoa; F13A7.3.1; F13A7.3.1; WBGene00005745.
DR GeneID; 184400; -.
DR KEGG; cel:CELE_F13A7.3; -.
DR UCSC; F13A7.3; c. elegans.
DR AGR; WB:WBGene00005745; -.
DR WormBase; F13A7.3; CE33049; WBGene00005745; srv-34.
DR eggNOG; ENOG502TH0A; Eukaryota.
DR GeneTree; ENSGT00970000197484; -.
DR HOGENOM; CLU_855858_0_0_1; -.
DR InParanoid; O45353; -.
DR OMA; YSQIAVV; -.
DR OrthoDB; 2882298at2759; -.
DR PhylomeDB; O45353; -.
DR Proteomes; UP000001940; Chromosome V.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008188; F:neuropeptide receptor activity; IBA:GO_Central.
DR GO; GO:0007218; P:neuropeptide signaling pathway; IBA:GO_Central.
DR CDD; cd00637; 7tm_classA_rhodopsin-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR019426; 7TM_GPCR_serpentine_rcpt_Srv.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR24238; G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR24238:SF26; G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF10323; 7TM_GPCR_Srv; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:CAB07575.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 52..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..280
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 326 AA; 37499 MW; 619B7E5DA829AA9B CRC64;
MLTPTWQMDL FIYEYFILIP IYIFILLGIL ITRNRHKTFQ SPYYTMMVSQ GLADVCTVTI
YIVIIGARYF SIGNVFIYNL SPYSSYSFSN TGPFMFTLRG VGVFFITTQR YLAVCRSHGT
LNYRLNQCPP LLIGFTHWLV AFLIYLPALL HTDIYFENEV TLLTVGSTTF VQWTSLTVMT
SYFVTCVSII IMYSQIAVVM VRARKVEQGV LTSTKTTKKL KDARLTLHVF ILVLFCIVTF
FFYIGEYVLA TDADNDRVRA LRLFYPTLSG NLSFINPIML LMMNRDVQSA FCCRFKVGLM
AENGREKPLP RPRVDLRSLC TRSGKV
//
