ID O45496_CAEEL Unreviewed; 328 AA.
AC O45496;
DT 01-JUN-1998, integrated into UniProtKB/TrEMBL.
DT 01-JUN-1998, sequence version 1.
DT 27-MAR-2024, entry version 139.
DE SubName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000313|EMBL:CAB07384.1};
GN ORFNames=CELE_F39B2.3 {ECO:0000313|EMBL:CAB07384.1}, F39B2.3
GN {ECO:0000313|EMBL:CAB07384.1, ECO:0000313|WormBase:F39B2.3};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CAB07384.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CAB07384.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAB07384.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
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DR EMBL; BX284601; CAB07384.1; -; Genomic_DNA.
DR PIR; T21985; T21985.
DR RefSeq; NP_493577.1; NM_061176.4.
DR AlphaFoldDB; O45496; -.
DR SMR; O45496; -.
DR STRING; 6239.F39B2.3.1; -.
DR EPD; O45496; -.
DR PaxDb; 6239-F39B2-3; -.
DR PeptideAtlas; O45496; -.
DR EnsemblMetazoa; F39B2.3.1; F39B2.3.1; WBGene00009554.
DR GeneID; 173346; -.
DR KEGG; cel:CELE_F39B2.3; -.
DR UCSC; F39B2.3; c. elegans.
DR AGR; WB:WBGene00009554; -.
DR WormBase; F39B2.3; CE16009; WBGene00009554; -.
DR eggNOG; KOG1198; Eukaryota.
DR GeneTree; ENSGT00940000154882; -.
DR HOGENOM; CLU_026673_3_1_1; -.
DR InParanoid; O45496; -.
DR OMA; KGMTAHY; -.
DR OrthoDB; 101972at2759; -.
DR PhylomeDB; O45496; -.
DR Proteomes; UP000001940; Chromosome I.
DR Bgee; WBGene00009554; Expressed in germ line (C elegans) and 4 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0003730; F:mRNA 3'-UTR binding; IBA:GO_Central.
DR GO; GO:0070402; F:NADPH binding; IBA:GO_Central.
DR GO; GO:0003960; F:NADPH:quinone reductase activity; IBA:GO_Central.
DR CDD; cd08253; zeta_crystallin; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR44154; QUINONE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR44154:SF1; QUINONE OXIDOREDUCTASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:O45496,
KW ECO:0007829|PeptideAtlas:O45496};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940}.
FT DOMAIN 19..324
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 328 AA; 35419 MW; 4D51E938C5388AEC CRC64;
MSKSICKSSM RAAVVRRFGA PDVIEAVESD MPRLEKNQVL VRNYAAGVNP VDTYIRAGQY
GKLPNLPYVP GKDGAGFVEL VGESVKNVKV GDRVWYGSEA DSTAEYVAVN RPFELPEGVS
FEEGASLGVP YLTAYRALFH LAGAKTGDVI LVHGASGGVG SALMQLAAWR NIEAVGTAGS
ADGIRFVKSL GARNVYNHSD KQYVSKMKND YPGGFNHIFE MAAHTNLNTD LGLLAPRGRV
AVIGNRAETT INARQLMVTE GAVYGVALGM SSEAELLDFG INIVSFLKET EFRPLINKLY
RLEQLGLAHE EIMNNKGAKG NLVVQIEH
//
