ID O45992_CAEEL Unreviewed; 481 AA.
AC O45992;
DT 01-JUN-1998, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 2.
DT 27-MAR-2024, entry version 137.
DE SubName: Full=Warthog protein 1 {ECO:0000313|EMBL:CAB03509.2};
GN Name=wrt-7 {ECO:0000313|EMBL:CAB03509.2,
GN ECO:0000313|WormBase:ZK1037.10};
GN ORFNames=CELE_ZK1037.10 {ECO:0000313|EMBL:CAB03509.2}, ZK1037.10
GN {ECO:0000313|WormBase:ZK1037.10};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CAB03509.2, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CAB03509.2, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAB03509.2,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
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DR EMBL; BX284605; CAB03509.2; -; Genomic_DNA.
DR PIR; T27665; T27665.
DR RefSeq; NP_506803.2; NM_074402.3.
DR AlphaFoldDB; O45992; -.
DR SMR; O45992; -.
DR STRING; 6239.ZK1037.10.1; -.
DR MEROPS; C46.A01; -.
DR PaxDb; 6239-ZK1037-10; -.
DR EnsemblMetazoa; ZK1037.10.1; ZK1037.10.1; WBGene00006953.
DR GeneID; 191504; -.
DR KEGG; cel:CELE_ZK1037.10; -.
DR UCSC; ZK1037.10; c. elegans.
DR AGR; WB:WBGene00006953; -.
DR WormBase; ZK1037.10; CE34137; WBGene00006953; wrt-7.
DR eggNOG; KOG3638; Eukaryota.
DR GeneTree; ENSGT00970000196193; -.
DR HOGENOM; CLU_034413_0_0_1; -.
DR InParanoid; O45992; -.
DR OMA; GHEDARY; -.
DR OrthoDB; 2880177at2759; -.
DR PhylomeDB; O45992; -.
DR Proteomes; UP000001940; Chromosome V.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
DR GO; GO:0016540; P:protein autoprocessing; IEA:InterPro.
DR CDD; cd00081; Hint; 1.
DR Gene3D; 2.170.16.10; Hedgehog/Intein (Hint) domain; 1.
DR InterPro; IPR001767; Hedgehog_Hint.
DR InterPro; IPR003586; Hint_dom_C.
DR InterPro; IPR003587; Hint_dom_N.
DR InterPro; IPR036844; Hint_dom_sf.
DR InterPro; IPR006141; Intein_N.
DR PANTHER; PTHR46706; PROTEIN QUA-1-RELATED; 1.
DR PANTHER; PTHR46706:SF12; PROTEIN QUA-1-RELATED; 1.
DR Pfam; PF01079; Hint; 1.
DR SMART; SM00305; HintC; 1.
DR SMART; SM00306; HintN; 1.
DR SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 1.
DR PROSITE; PS50817; INTEIN_N_TER; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..481
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004158382"
FT DOMAIN 272..382
FT /note="Hint"
FT /evidence="ECO:0000259|SMART:SM00306"
FT DOMAIN 386..430
FT /note="Hint"
FT /evidence="ECO:0000259|SMART:SM00305"
SQ SEQUENCE 481 AA; 54513 MW; 4CE81DB2D0AAA962 CRC64;
MNISKCVLVV ALLSLCCKLS FGSSCGETTI PFSFEILPTG QPVLGCARPT CFGWDPKGYH
LPTDARFVRI DRKRDGFLRD DPIYTYPFTP DGSKMYLQQN STCEPAFQSA MCDSKIQWVG
GVEPVQDVNS THDIAYQCCT YPPLRESTDR GMTLVAAGQI VIGGEVFKNG SQYAFDYISN
IAKNIDEYGK IFYEVNVRRL ACLDPHNADR SVDEIWDSEN TIRKVNGKKA MAHQVPNVAV
GNAVPQYNVY PAVAQQPAPY SYLPAAPQCQ QYYCFPNDAV VNVYEKAVKR MDELEIGDWV
EALDENGEDI TFLPVKYWLH RDPEQEAEFL EFSLDNGETF TLTEKHLVYT TECRQNSSEL
KISWESISAG KVNAGDCFYL AQSEALTKYR LVEILDIKRV KKTGIYAPMT SQGHLLVNKI
HTSCHSEVDH HILQNSFFKH VLKWKNKITK YFWSYETERN IGQSLNSLIA IFNLVVPSNM
Y
//
