ID O46405_BOVIN Unreviewed; 296 AA.
AC O46405; F1MHN6;
DT 01-JUN-1998, integrated into UniProtKB/TrEMBL.
DT 01-JUN-1998, sequence version 1.
DT 27-MAR-2024, entry version 148.
DE SubName: Full=CD80 anitgen {ECO:0000313|EMBL:CAA71081.1};
DE Flags: Fragment;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|EMBL:CAA71081.1};
RN [1] {ECO:0000313|EMBL:CAA71081.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=9914337; DOI=10.1007/s002510050484;
RA Parsons K.R., Howard C.J.;
RT "Cloning of cattle CD80.";
RL Immunogenetics 49:231-234(1999).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; Y09950; CAA71081.1; -; mRNA.
DR RefSeq; NP_001193368.1; NM_001206439.1.
DR RefSeq; XP_005201324.1; XM_005201267.3.
DR RefSeq; XP_010799376.1; XM_010801074.2.
DR AlphaFoldDB; O46405; -.
DR SMR; O46405; -.
DR GeneID; 407131; -.
DR KEGG; bta:407131; -.
DR CTD; 941; -.
DR eggNOG; ENOG502S5B5; Eukaryota.
DR HOGENOM; CLU_071073_2_0_1; -.
DR TreeFam; TF351094; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015026; F:coreceptor activity; IEA:InterPro.
DR GO; GO:0031295; P:T cell costimulation; IEA:InterPro.
DR CDD; cd16083; IgC1_CD80; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR037676; CD80_IgC.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR25466; T-LYMPHOCYTE ACTIVATION ANTIGEN; 1.
DR PANTHER; PTHR25466:SF4; T-LYMPHOCYTE ACTIVATION ANTIGEN CD80; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00407; IGc1; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 247..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 46..135
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 146..229
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT NON_TER 296
FT /evidence="ECO:0000313|EMBL:CAA71081.1"
SQ SEQUENCE 296 AA; 33618 MW; 7ADB11FB5F532EF5 CRC64;
MGHTMKWGTL PPKRPCLWLS QLLVLTGLFY FCSGITPKSV TKRVKETVML SCDYNTSTEE
LTSLRIYWQK DSKMVLAILP GKVQVWPEYK NRTITDMNDN PRIVILALRL SDSGTYTCVI
QKPDLKGAYK LEHLTSVRLM IRADFPVPTI NDLGNPSPNI RRLICSTSGG FPRPHLYWLE
NGEELNATNT TLSQDPETKL YMISSELDFN MTSNHSFLCL VKYGDLTVSQ TFYWQESKPT
PSANQHLTWT IIIPVSAFGI SVIIAVILTC LTCRNAAIRR QRRENEVEME SCSQSP
//
