ID O53329_MYCTU Unreviewed; 429 AA.
AC O53329; I6YBE7; L0TEI6;
DT 01-JUN-1998, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 3.
DT 27-MAR-2024, entry version 122.
DE SubName: Full=Conserved protein {ECO:0000313|EMBL:CCP45990.1};
GN OrderedLocusNames=Rv3179 {ECO:0000313|EMBL:CCP45990.1};
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332 {ECO:0000313|EMBL:CCP45990.1, ECO:0000313|Proteomes:UP000001584};
RN [1] {ECO:0000313|EMBL:CCP45990.1, ECO:0000313|Proteomes:UP000001584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv {ECO:0000313|Proteomes:UP000001584};
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III., Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L., Oliver K., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
RA Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2] {ECO:0007829|PubMed:21969609}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21969609; DOI=10.1074/mcp.M111.011445;
RA Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT mass spectrometry.";
RL Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
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DR EMBL; AL123456; CCP45990.1; -; Genomic_DNA.
DR RefSeq; NP_217695.1; NC_000962.3.
DR RefSeq; WP_003416640.1; NZ_NVQJ01000019.1.
DR AlphaFoldDB; O53329; -.
DR STRING; 83332.Rv3179; -.
DR PaxDb; 83332-Rv3179; -.
DR DNASU; 887947; -.
DR GeneID; 45427168; -.
DR GeneID; 887947; -.
DR KEGG; mtu:Rv3179; -.
DR PATRIC; fig|83332.111.peg.3540; -.
DR eggNOG; COG1373; Bacteria.
DR InParanoid; O53329; -.
DR OrthoDB; 128089at2; -.
DR PhylomeDB; O53329; -.
DR Proteomes; UP000001584; Chromosome.
DR InterPro; IPR041682; AAA_14.
DR InterPro; IPR025420; DUF4143.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43566; CONSERVED PROTEIN; 1.
DR PANTHER; PTHR43566:SF2; DUF4143 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13173; AAA_14; 1.
DR Pfam; PF13635; DUF4143; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 1: Evidence at protein level;
KW Reference proteome {ECO:0000313|Proteomes:UP000001584}.
FT DOMAIN 27..144
FT /note="AAA"
FT /evidence="ECO:0000259|Pfam:PF13173"
FT DOMAIN 210..371
FT /note="DUF4143"
FT /evidence="ECO:0000259|Pfam:PF13635"
SQ SEQUENCE 429 AA; 48053 MW; B662D9374654987C CRC64;
MVHDEAGHEL IERHMLEQLR EVAEYTRVVL INGPRQAGKT TLLQQLHAEL GGWLRSLDVD
VERASARADP EGYIMSAPRP TFLDEVQCAG DPLILAIKTA TDRDRRPRQF FLSGSTRFLT
VPTLSESLAG RVAILDLWPL SVAERSGVRP EIIAQLFTEP QVVLGTEPAP VTRHEYLQLA
CAGGFPEVVQ RPAGRARSRW FSDYLRTVTQ RDVRELKRIE QTDRLPRFMR YLAAITAQEL
NVAEAARVIG VDAGTIRSDL ALFETVYLVH RLPAWSRNLT AKIKKRSKIH VVDSGFAAWL
RGQSADSLAR PTAEGAGPIM ETFVINELMK LRAATELEVD LYHFRDRDGR EIDCILQTPD
SRVVGVEVKA SATVNVHDFR HLSFARDRLG DEFITGVLFY TGARALPFGD RLMALPINLL
WNGQSVSSL
//
