ID O53337_MYCTU Unreviewed; 344 AA.
AC O53337; I6X6M3; Q7D5Y9;
DT 01-JUN-1998, integrated into UniProtKB/TrEMBL.
DT 01-JUN-1998, sequence version 1.
DT 27-MAR-2024, entry version 146.
DE SubName: Full=Probable transposase {ECO:0000313|EMBL:CCP46003.1};
GN OrderedLocusNames=Rv3191c {ECO:0000313|EMBL:CCP46003.1};
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332 {ECO:0000313|EMBL:CCP46003.1, ECO:0000313|Proteomes:UP000001584};
RN [1] {ECO:0000313|EMBL:CCP46003.1, ECO:0000313|Proteomes:UP000001584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv {ECO:0000313|Proteomes:UP000001584};
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III., Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L., Oliver K., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
RA Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
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DR EMBL; AL123456; CCP46003.1; -; Genomic_DNA.
DR RefSeq; NP_217707.1; NC_000962.3.
DR RefSeq; WP_003416786.1; NZ_NVQJ01000003.1.
DR AlphaFoldDB; O53337; -.
DR STRING; 83332.Rv3191c; -.
DR PaxDb; 83332-Rv3191c; -.
DR DNASU; 887628; -.
DR GeneID; 887628; -.
DR KEGG; mtu:Rv3191c; -.
DR PATRIC; fig|83332.111.peg.3557; -.
DR TubercuList; Rv3191c; -.
DR eggNOG; COG2826; Bacteria.
DR InParanoid; O53337; -.
DR OrthoDB; 9803231at2; -.
DR PhylomeDB; O53337; -.
DR Proteomes; UP000001584; Chromosome.
DR GO; GO:0005829; C:cytosol; HDA:MTBBASE.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004803; F:transposase activity; IBA:GO_Central.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR GO; GO:0052562; P:suppression by symbiont of host immune response; IDA:MTBBASE.
DR GO; GO:0032196; P:transposition; IBA:GO_Central.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR025246; IS30-like_HTH.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR NCBIfam; NF033563; transpos_IS30; 1.
DR PANTHER; PTHR10948; TRANSPOSASE; 1.
DR PANTHER; PTHR10948:SF23; TRANSPOSASE INSI FOR INSERTION SEQUENCE ELEMENT IS30A-RELATED; 1.
DR Pfam; PF13936; HTH_38; 1.
DR Pfam; PF00665; rve; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001584}.
FT DOMAIN 175..334
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 134..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..158
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 344 AA; 40304 MW; 09869B8D316DF74A CRC64;
MRQISSRYLS EEERINIADL RRSGLSIRKI ADQLGRAPST VSRELRRNSR RDGQYRPFEA
HRWAVQRRVR RHRRRIDKNP DLCELIAELL AQRWSPQQIA RHLRRKYPDD RSMWLCHESI
YQAVYQPQSR LIRPPQVKSP HRGPLRTGRT HRRAHLRPGR RRPRFAQPML SIHQRPFDPA
DRSEPGHWEG DLIVGKNQGS AIGTLVERQT RLIRLLHLPT HDAYCLRIAI TETMSDLPVT
LVRSITWDQG IEMARHIDIT ADLGAPVYFC DSRSPWQRAS NENSNGLLRQ YFPKGTSLST
YTPDHLRAVE YEINNRPRQV LGHRSPAELF TALLTSPDHQ LLRR
//
