ID O61706_CAEEL Unreviewed; 599 AA.
AC O61706;
DT 01-AUG-1998, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 2.
DT 24-JAN-2024, entry version 137.
DE SubName: Full=Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 {ECO:0000313|EMBL:CCD73346.1};
GN ORFNames=CELE_R119.5 {ECO:0000313|EMBL:CCD73346.1}, R119.5
GN {ECO:0000313|EMBL:CCD73346.1, ECO:0000313|WormBase:R119.5a};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD73346.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CCD73346.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCD73346.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. L-
CC isoaspartyl/D-aspartyl protein methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005369}.
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DR EMBL; BX284601; CCD73346.1; -; Genomic_DNA.
DR RefSeq; NP_001248848.1; NM_001261919.1.
DR AlphaFoldDB; O61706; -.
DR SMR; O61706; -.
DR STRING; 6239.R119.5a.1; -.
DR PaxDb; 6239-R119-5a; -.
DR EnsemblMetazoa; R119.5a.1; R119.5a.1; WBGene00020090.
DR GeneID; 171631; -.
DR UCSC; R119.5; c. elegans.
DR AGR; WB:WBGene00020090; -.
DR WormBase; R119.5a; CE44884; WBGene00020090; -.
DR eggNOG; KOG1661; Eukaryota.
DR GeneTree; ENSGT00950000183032; -.
DR HOGENOM; CLU_455788_0_0_1; -.
DR InParanoid; O61706; -.
DR OrthoDB; 55859at2759; -.
DR Proteomes; UP000001940; Chromosome I.
DR Bgee; WBGene00020090; Expressed in pharyngeal muscle cell (C elegans) and 3 other cell types or tissues.
DR ExpressionAtlas; O61706; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IBA:GO_Central.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000682; PCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR11579; PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11579:SF9; PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN; 1.
DR Pfam; PF01135; PCMT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001940}.
FT REGION 452..538
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 482..511
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..538
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 599 AA; 68914 MW; DFF405118342C32D CRC64;
MGNSESQNDD LIDFLVKNDT IRRRNIERAF RLVDRSDFLP ISERKFTRLP SLTSTEPGGP
FYPGALRVGA IDIYAKLFDY LDLRKGHSFL HIGTGSGYLS TIAGILLGET GINHGIELYE
NLVTYSETCI DQWITTPEAS SVGWARPELK VCDITDVKFL EAHQNRYDRI FVGFVADDSQ
LLKRMLGMLN VGGQLVMPRI QGVCRYRRVS KHRTVYDVPG RMTFSPMIRL PKEERISTPT
PFESGPRTLT YLARQALRRD IRRHAYNPRV NRQICGSIMV MKGGNTYMDH VQRHQAEQFE
ELNRRRQLFD PRPIDQLTPA DNQLTDQRTR NHLDDVMDQY LGRNNNPREQ ENNEQNIRNT
IADHVRRWNE TRTDVLQEML NWREMQGFTA PRAHLDGANL RNTAPATENR AAPAYVLEWT
INHDRPRHHR ILSSIARPET PNTPRMEIVM IPNINDPSTT GLVERPNGDL SEDEQELSDA
LEEPQESPST STESQVSEDE EPCCSTDPAS TTSRRRRIRS PKSESAKKPR KSSSPPLDDY
LKEMAVRQNH EQRAIHLRQR RNLEIAGADG VYQRIIDELP LPPTLKDYVR LVQHEVVLK
//
