ID O61894_CAEEL Unreviewed; 840 AA.
AC O61894;
DT 01-AUG-1998, integrated into UniProtKB/TrEMBL.
DT 01-AUG-1998, sequence version 1.
DT 27-MAR-2024, entry version 136.
DE SubName: Full=SSD domain-containing protein {ECO:0000313|EMBL:CCD66561.1};
GN Name=ptr-15 {ECO:0000313|EMBL:CCD66561.1,
GN ECO:0000313|WormBase:T07H8.6};
GN ORFNames=CELE_T07H8.6 {ECO:0000313|EMBL:CCD66561.1}, T07H8.6
GN {ECO:0000313|WormBase:T07H8.6};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD66561.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CCD66561.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCD66561.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SIMILARITY: Belongs to the patched family.
CC {ECO:0000256|ARBA:ARBA00005585}.
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DR EMBL; BX284605; CCD66561.1; -; Genomic_DNA.
DR PIR; T33217; T33217.
DR RefSeq; NP_504760.1; NM_072359.3.
DR AlphaFoldDB; O61894; -.
DR SMR; O61894; -.
DR STRING; 6239.T07H8.6.2; -.
DR EPD; O61894; -.
DR PaxDb; 6239-T07H8-6; -.
DR EnsemblMetazoa; T07H8.6.1; T07H8.6.1; WBGene00004229.
DR GeneID; 191749; -.
DR KEGG; cel:CELE_T07H8.6; -.
DR UCSC; T07H8.6; c. elegans.
DR AGR; WB:WBGene00004229; -.
DR WormBase; T07H8.6; CE18227; WBGene00004229; ptr-15.
DR eggNOG; KOG1934; Eukaryota.
DR HOGENOM; CLU_002359_2_1_1; -.
DR InParanoid; O61894; -.
DR OMA; SIGLCID; -.
DR OrthoDB; 5491217at2759; -.
DR PhylomeDB; O61894; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00004229; Expressed in embryo and 3 other cell types or tissues.
DR GO; GO:0030659; C:cytoplasmic vesicle membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0006897; P:endocytosis; IBA:GO_Central.
DR GO; GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR003392; Ptc/Disp.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR PANTHER; PTHR10796:SF105; SSD DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02460; Patched; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 33..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 678..698
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 704..726
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 733..752
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 772..794
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 806..825
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 262..419
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 840 AA; 95187 MW; 65C04A41D79CC327 CRC64;
MKLRIRNPSG ILQEYLAHLF YQYGLFIYDR PRFFTLGPLI LTIIFSFGIL NMRTEDDLRF
LYSPEHSLSR EEYQVHKDFS GDSKNNSFVS ITIQTSSEDK NLLKKDLAQK LIQLNKYVLE
KMEIQVDGKI INFGKEVCSR MKQCELSNTI ATIFLDTFWS EKLRKDPRIK IEYPTMKFFD
NKFFLPTHFY GVQPGGPLGI ESIDMVHFVY QIPAYNEHTS EEMSKIFEQS LTALLENQTT
FDTSMFSLSI LKDEMQKNST YTMPFISLTI LLLLCFTVAS CMTDNWVTSK PIEAMIGILV
SSMAIVSAGG LLFALGVPFI NQVTVMPFIA LAIGVDDVYV MLGAWQDTRR TLDAKKRMGL
ALEEAGSAIT VTSLTSVLSF GIGTYSTTPA IAIFCKFIAL AIMFDWFYQL TFFAAVMAMG
AKREAAGYHC VFVWKRCDRE EIAKAKNENA ISPTRYFFEN IFAPFICRPS VRFCMLNLYV
VYIAIAFYGC SQLTPNLTPS QLVVDDSPLV PYLNLAEKKI WAEGLIGRIY VNNAPDFSKN
PEMVDRMLQM VNELESTPYS MGPNSTNFWL NEFNNYRQFF FQEDAKFYET LKSFLKVSFN
SHWETDLVWD TPDKSSKGGT KVEKFVFTTA FKISNWNIRT SLLLTWRNIT SSYPEFDALV
FDENNFYSDQ MLELQSTILS SLGTAIILLS AICIMFIAES YIVFWVVCTL ISMDIGTAGL
LSLWGADLDP MTVVNILMSI GQCIDFATHV GIRIYRSEYS DPDERIRDAM GAIGWPVVQA
GTSTLLAIVV MLMVPSSAVR MFARTSVLVV GTGFFHGLII LPIIVRSFAT NAKALAPSNH
//
