ID O66459_AQUAE Unreviewed; 409 AA.
AC O66459;
DT 01-AUG-1998, integrated into UniProtKB/TrEMBL.
DT 01-AUG-1998, sequence version 1.
DT 27-MAR-2024, entry version 131.
DE SubName: Full=Cytochrome b {ECO:0000313|EMBL:AAC06424.1};
GN Name=petB {ECO:0000313|EMBL:AAC06424.1};
GN OrderedLocusNames=aq_044 {ECO:0000313|EMBL:AAC06424.1};
OS Aquifex aeolicus (strain VF5).
OC Bacteria; Aquificota; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX NCBI_TaxID=224324 {ECO:0000313|EMBL:AAC06424.1, ECO:0000313|Proteomes:UP000000798};
RN [1] {ECO:0000313|EMBL:AAC06424.1, ECO:0000313|Proteomes:UP000000798}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VF5 {ECO:0000313|EMBL:AAC06424.1,
RC ECO:0000313|Proteomes:UP000000798};
RX PubMed=9537320; DOI=10.1038/32831;
RA Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA Feldman R.A., Short J.M., Olson G.J., Swanson R.V.;
RT "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL Nature 392:353-358(1998).
RN [2] {ECO:0007829|PDB:6KLS, ECO:0007829|PDB:6KLV}
RP STRUCTURE BY ELECTRON MICROSCOPY (3.20 ANGSTROMS).
RX PubMed=31778296; DOI=10.1002/anie.201911554;
RA Zhu G., Zeng H., Zhang S., Juli J., Pang X., Hoffmann J., Zhang Y.,
RA Morgner N., Zhu Y., Peng G., Michel H., Sun F.;
RT "A 3.3A-Resolution Structure of Hyperthermophilic Respiratory ComplexIII
RT Reveals the Mechanism of Its Thermal Stability.";
RL Angew. Chem. Int. Ed. 59:343-351(2020).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AE000657; AAC06424.1; -; Genomic_DNA.
DR PIR; H70303; H70303.
DR RefSeq; NP_213019.1; NC_000918.1.
DR RefSeq; WP_010879957.1; NC_000918.1.
DR PDB; 6KLS; EM; 3.30 A; B/E=1-409.
DR PDB; 6KLV; EM; 3.20 A; B/E=1-409.
DR AlphaFoldDB; O66459; -.
DR EMDB; EMD-0716; -.
DR EMDB; EMD-0719; -.
DR SMR; O66459; -.
DR STRING; 224324.aq_044; -.
DR EnsemblBacteria; AAC06424; AAC06424; aq_044.
DR KEGG; aae:aq_044; -.
DR PATRIC; fig|224324.8.peg.35; -.
DR eggNOG; COG1290; Bacteria.
DR HOGENOM; CLU_031114_3_0_0; -.
DR InParanoid; O66459; -.
DR OrthoDB; 9804503at2; -.
DR Proteomes; UP000000798; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0022904; P:respiratory electron transport chain; IEA:InterPro.
DR InterPro; IPR005798; Cyt_b/b6_C.
DR InterPro; IPR036150; Cyt_b/b6_C_sf.
DR InterPro; IPR005797; Cyt_b/b6_N.
DR InterPro; IPR027387; Cytb/b6-like_sf.
DR InterPro; IPR016174; Di-haem_cyt_TM.
DR PANTHER; PTHR19271; CYTOCHROME B; 1.
DR PANTHER; PTHR19271:SF16; CYTOCHROME B; 1.
DR Pfam; PF00032; Cytochrom_B_C; 1.
DR Pfam; PF13631; Cytochrom_B_N_2; 1.
DR SUPFAM; SSF81648; a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase); 1.
DR SUPFAM; SSF81342; Transmembrane di-heme cytochromes; 1.
DR PROSITE; PS51003; CYTB_CTER; 1.
DR PROSITE; PS51002; CYTB_NTER; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:6KLS, ECO:0007829|PDB:6KLV};
KW Electron transport {ECO:0000256|ARBA:ARBA00022982};
KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000798};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 38..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..229
FT /note="Cytochrome b/b6 N-terminal region profile"
FT /evidence="ECO:0000259|PROSITE:PS51002"
FT DOMAIN 235..404
FT /note="Cytochrome b/b6 C-terminal region profile"
FT /evidence="ECO:0000259|PROSITE:PS51003"
SQ SEQUENCE 409 AA; 46928 MW; E524BE04CC06607A CRC64;
MGLIEKIVDW IDERAHVREI YRTQMVEYKV AKNLTFPYVF GILALVTFAI QIISGMVLIL
YYNLQSQTLL TVHLLDNGRN SLRMALQAHT RTGANFFMAI VYLHMFTGIY YNAYKRPREL
VWIVGWLIYF VLILTALSGY LLPWGQLSYW GFIVTTEIPG SLADAPILKP IFKAIAETIV
LWMKGGYVVT DVTLGRVFGS HVLIYPLILL ALVGIHLYLV RAAGISNPEG IEYDKKKNPD
KFVPFHPYMT LKEGAYVMWY LAVFFFFVFF HISHFLPPEN FEPANPLKTP AHIAPEWYLL
GYYEVFRSIP SKFWGFVAFN ALLLLLLLLP FLDFSPLKSA RRRPLFFVMF VIFMISSMAL
TILGTMPPTP QNAKLGLIFA ALVFAFFISL PIISFIEYGW YKAKGGQQE
//
