ID O69637_MYCTU Unreviewed; 172 AA.
AC O69637; F2GFB1; I6X815;
DT 01-AUG-1998, integrated into UniProtKB/TrEMBL.
DT 01-AUG-1998, sequence version 1.
DT 27-MAR-2024, entry version 118.
DE SubName: Full=Probable conserved transmembrane protein {ECO:0000313|EMBL:CCP46492.1};
GN OrderedLocusNames=Rv3669 {ECO:0000313|EMBL:CCP46492.1};
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332 {ECO:0000313|EMBL:CCP46492.1, ECO:0000313|Proteomes:UP000001584};
RN [1] {ECO:0000313|EMBL:CCP46492.1, ECO:0000313|Proteomes:UP000001584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv {ECO:0000313|Proteomes:UP000001584};
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III., Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L., Oliver K., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
RA Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2] {ECO:0007829|PubMed:21969609}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21969609; DOI=10.1074/mcp.M111.011445;
RA Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT mass spectrometry.";
RL Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
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DR EMBL; AL123456; CCP46492.1; -; Genomic_DNA.
DR RefSeq; NP_218186.1; NC_000962.3.
DR RefSeq; WP_003419710.1; NZ_NVQJ01000028.1.
DR AlphaFoldDB; O69637; -.
DR SMR; O69637; -.
DR STRING; 83332.Rv3669; -.
DR PaxDb; 83332-Rv3669; -.
DR DNASU; 885626; -.
DR GeneID; 885626; -.
DR KEGG; mtu:Rv3669; -.
DR PATRIC; fig|83332.111.peg.4080; -.
DR eggNOG; ENOG50332VJ; Bacteria.
DR InParanoid; O69637; -.
DR OrthoDB; 3828498at2; -.
DR PhylomeDB; O69637; -.
DR Proteomes; UP000001584; Chromosome.
DR GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
DR InterPro; IPR009937; Phage_holin_3_6.
DR Pfam; PF07332; Phage_holin_3_6; 1.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001584};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|EMBL:CCP46492.1};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 69..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 145..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 172 AA; 18919 MW; 2136C74C5C9190FE CRC64;
MSKIDRKNGV PSTLTTIPLA DPHAGPAEPS IGDLIKDATT QMSTLVRAEV ELARAEITRD
VKKGLTGSVF FISSLVVGFY STFFFFFFVA ELLDTWIWRW VAFLLVFAIM VVVTAVLALL
GFLKVRRIRG PRQTIASVKE TRTALTPGHD KTPVTPKPVT SDRATPVDPS GW
//
