ID O84414_CHLTR Unreviewed; 453 AA.
AC O84414;
DT 01-NOV-1998, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1998, sequence version 1.
DT 27-MAR-2024, entry version 107.
DE SubName: Full=Amino acid permease {ECO:0000313|EMBL:AAC68006.1};
GN OrderedLocusNames=CT_409 {ECO:0000313|EMBL:AAC68006.1};
OS Chlamydia trachomatis (strain D/UW-3/Cx).
OC Bacteria; Chlamydiota; Chlamydiia; Chlamydiales; Chlamydiaceae;
OC Chlamydia/Chlamydophila group; Chlamydia.
OX NCBI_TaxID=272561 {ECO:0000313|EMBL:AAC68006.1, ECO:0000313|Proteomes:UP000000431};
RN [1] {ECO:0000313|EMBL:AAC68006.1, ECO:0000313|Proteomes:UP000000431}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D/UW-3/Cx {ECO:0000313|Proteomes:UP000000431};
RX PubMed=9784136; DOI=10.1126/science.282.5389.754;
RA Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L.,
RA Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W.;
RT "Genome sequence of an obligate intracellular pathogen of humans: Chlamydia
RT trachomatis.";
RL Science 282:754-759(1998).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC ECO:0000256|RuleBase:RU363064}.
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DR EMBL; AE001273; AAC68006.1; -; Genomic_DNA.
DR PIR; C71518; C71518.
DR RefSeq; NP_219919.1; NC_000117.1.
DR RefSeq; WP_010725188.1; NC_000117.1.
DR AlphaFoldDB; O84414; -.
DR STRING; 272561.CT_409; -.
DR EnsemblBacteria; AAC68006; AAC68006; CT_409.
DR GeneID; 884707; -.
DR KEGG; ctr:CT_409; -.
DR PATRIC; fig|272561.5.peg.440; -.
DR HOGENOM; CLU_024867_1_2_0; -.
DR InParanoid; O84414; -.
DR OrthoDB; 9804874at2; -.
DR Proteomes; UP000000431; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR001463; Na/Ala_symport.
DR NCBIfam; TIGR00835; agcS; 1.
DR PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR PANTHER; PTHR30330:SF3; TRANSCRIPTIONAL REGULATOR, LRP FAMILY-RELATED; 1.
DR Pfam; PF01235; Na_Ala_symp; 1.
DR PRINTS; PR00175; NAALASMPORT.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU363064};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW Reference proteome {ECO:0000313|Proteomes:UP000000431};
KW Symport {ECO:0000256|RuleBase:RU363064};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363064};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363064};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT TRANSMEM 15..33
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 73..95
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 101..118
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 151..174
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 186..204
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 243..267
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 303..328
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 348..372
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 388..405
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 411..430
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
SQ SEQUENCE 453 AA; 49337 MW; 3BB507C95FAAC86D CRC64;
MSAFLSFLTA FDDFIWSYIA FVLILLLGVL FTCKSKFAQF TQLPAFFKLF YHFSKEASSK
KENQKKGVHP LKVFFASAGG NIGIGNVVGI VTAASVGGPG ALFWVWIAGI LGSIVKYSEV
YLGIKFRQSD ANNVYHGGPM FFLDKAYRTR IVSVIVAVLL CIYGVEIYQF SIIANTLASC
WDVPKLMAIA SLLFLVMYAV QGGLQRIGKI CSLVLPFFML VYCGMAFYIL IQEIHTLPAL
FSSIFRSAFT GHGAIGGFAG CTVASTIRQG LSRAAYSGDI GIGFDSIIQS ETSATNPQTQ
AQLSIVGVIV DNLVCTLSLL IVLASGVWHR AGLEGSEIVE QALSFYFPYI RVFLPAFLFA
TGYTTIISYF LVGKKCANFI CGNKGSKFYT VYGIIALPAF CFLPQDTALL VMSVSGALLL
CLNLLGVFLM RKELIFPKKE AETLEVSEST LSS
//
