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Database: UniProt
Entry: O94256
LinkDB: O94256
Original site: O94256 
ID   SET6_SCHPO              Reviewed;         483 AA.
AC   O94256;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   16-JAN-2019, entry version 101.
DE   RecName: Full=SET domain and MYND-type zinc finger protein 6;
DE            EC=2.1.1.-;
GN   Name=set6; ORFNames=SPBP8B7.07c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales;
OC   Schizosaccharomycetaceae; Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M.,
RA   Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A.,
RA   Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G.,
RA   Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K.,
RA   James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J.,
RA   Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C.,
RA   Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E.,
RA   Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S.,
RA   Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K.,
RA   Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S.,
RA   Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B.,
RA   Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S.,
RA   Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D.,
RA   Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R.,
RA   Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B.,
RA   Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S.,
RA   Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M.,
RA   Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G.,
RA   Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J.,
RA   Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L.,
RA   Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J.,
RA   Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the
RT   fission yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
CC       Nucleus {ECO:0000269|PubMed:16823372}. Note=Localizes to
CC       chromatin.
CC   -!- SIMILARITY: Belongs to the class V-like SAM-binding
CC       methyltransferase superfamily. {ECO:0000255|PROSITE-
CC       ProRule:PRU00190}.
DR   EMBL; CU329671; CAA21792.1; -; Genomic_DNA.
DR   PIR; T40801; T40801.
DR   RefSeq; NP_596514.1; NM_001022435.2.
DR   ProteinModelPortal; O94256; -.
DR   BioGrid; 277881; 25.
DR   STRING; 4896.SPBP8B7.07c.1; -.
DR   MaxQB; O94256; -.
DR   PaxDb; O94256; -.
DR   PRIDE; O94256; -.
DR   EnsemblFungi; SPBP8B7.07c.1; SPBP8B7.07c.1:pep; SPBP8B7.07c.
DR   GeneID; 2541370; -.
DR   KEGG; spo:SPBP8B7.07c; -.
DR   EuPathDB; FungiDB:SPBP8B7.07c; -.
DR   PomBase; SPBP8B7.07c; set6.
DR   InParanoid; O94256; -.
DR   KO; K11426; -.
DR   OMA; ACKDYLM; -.
DR   PhylomeDB; O94256; -.
DR   Reactome; R-SPO-3214841; PKMTs methylate histone lysines.
DR   PRO; PR:O94256; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0000790; C:nuclear chromatin; IC:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; ISM:PomBase.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016570; P:histone modification; NAS:PomBase.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR002893; Znf_MYND.
DR   Pfam; PF00856; SET; 1.
DR   Pfam; PF01753; zf-MYND; 1.
DR   SMART; SM00317; SET; 1.
DR   PROSITE; PS50280; SET; 1.
DR   PROSITE; PS01360; ZF_MYND_1; 1.
DR   PROSITE; PS50865; ZF_MYND_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Metal-binding; Methyltransferase;
KW   Nucleus; Reference proteome; S-adenosyl-L-methionine; Transferase;
KW   Zinc; Zinc-finger.
FT   CHAIN         1    483       SET domain and MYND-type zinc finger
FT                                protein 6.
FT                                /FTId=PRO_0000316541.
FT   DOMAIN        4    228       SET. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00190}.
FT   ZN_FING      49     87       MYND-type. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00134}.
SQ   SEQUENCE   483 AA;  55047 MW;  2AE07BA1675F2CF2 CRC64;
     MDAPLIASVI LPEFGKGTVA TDNIPIGKII IRKRVDILSL DSANLTRTCS TCTEEKVKTQ
     RCAACKIIHY CSKGCQKADW PFHKLECKAL QASKQNGILP SVCRLLIRLY LLWQKNPAII
     EPMEGHQNEF QAVSSSWSDA ELIASAASHY TQIYQAELFQ KLFCRLAVNA MNLVTSSFDS
     LGMCLDTILC RLNHSCDPNC QIIFDGAIVQ LVSKRDIKKD EQLFISYIDI RLPKSIRQKQ
     LLKKYFFSCY CPRCENDHTT KETDGSKWMG RLRNSKSLMK NLAMARDLWS CGWKQTAFPW
     SNLLHHIKLG MLDESNFNGA FAALYLKSSA DEFLDALHVV DEYQLLLLGK QVAMEVKHLM
     FPNDKPLEME FPSSSQPQQT VPTNNSLFLL KNIPSFGGLH HCILGRYSIS LDDFVLWLLD
     RAQRLQQAVR ISHPSTTFCS NVENDIKEIF EVCKDYCMLH VQNNLKAFEE KLWAACKDFL
     VTY
//
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