ID YGD6_SCHPO Reviewed; 346 AA.
AC O94564;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 24-JAN-2024, entry version 130.
DE RecName: Full=Zinc-type alcohol dehydrogenase-like protein C1773.06c;
DE EC=1.-.-.-;
GN ORFNames=SPBC1773.06c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. Quinone oxidoreductase subfamily. {ECO:0000305}.
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DR EMBL; CU329671; CAA21911.1; -; Genomic_DNA.
DR PIR; T39671; T39671.
DR RefSeq; NP_595121.1; NM_001021028.2.
DR AlphaFoldDB; O94564; -.
DR SMR; O94564; -.
DR BioGRID; 276676; 12.
DR STRING; 284812.O94564; -.
DR MaxQB; O94564; -.
DR PaxDb; 4896-SPBC1773-06c-1; -.
DR EnsemblFungi; SPBC1773.06c.1; SPBC1773.06c.1:pep; SPBC1773.06c.
DR GeneID; 2540139; -.
DR KEGG; spo:SPBC1773.06c; -.
DR PomBase; SPBC1773.06c; -.
DR VEuPathDB; FungiDB:SPBC1773.06c; -.
DR eggNOG; KOG1198; Eukaryota.
DR HOGENOM; CLU_026673_3_4_1; -.
DR InParanoid; O94564; -.
DR OMA; YEYMWAR; -.
DR PhylomeDB; O94564; -.
DR PRO; PR:O94564; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0004022; F:alcohol dehydrogenase (NAD+) activity; ISM:PomBase.
DR GO; GO:0006066; P:alcohol metabolic process; IC:PomBase.
DR GO; GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.
DR CDD; cd08276; MDR7; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR45033; -; 1.
DR PANTHER; PTHR45033:SF2; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C1773.06C; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Oxidoreductase; Reference proteome.
FT CHAIN 1..346
FT /note="Zinc-type alcohol dehydrogenase-like protein
FT C1773.06c"
FT /id="PRO_0000339117"
SQ SEQUENCE 346 AA; 37321 MW; 8CC3554C771DE0E7 CRC64;
MALRYVVHDE ISGFDQLKPE EYEVPQKLNP GEVLVKLKAA SLNYRDLIIT KGLYPLPLQL
PVVPGSDGAG IIEKVGEDVE GFEKGDSVVC NFFTNYLDGT PTDFATHSAL GGTRDGCFQK
YAVLPAHALV HAPKNLSFEE IATLPCAAVT AWNGLFGSKE HQVKPGNNVL VLGTGGVSTF
ALQFALAAGA NVTVTSSSDE KLEFAKKLGA THTINYKKTP QWASPALKMT NGVGYHHVIE
VGGEKTLPQS IACLAKDGMI SMIGFVASEG TTPNLTSIIG QILNRNANIR GIFVGSVSMF
RDMVACIEAK DIHPVVDKVF PFDQLKEAYE YQWSQAHIGK VVLKID
//
