ID OMPD_SALTY Reviewed; 362 AA.
AC P37592;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 13-DEC-2001, sequence version 2.
DT 27-MAR-2024, entry version 146.
DE RecName: Full=Outer membrane porin protein OmpD;
DE Flags: Precursor;
GN Name=ompD; Synonyms=nmpC; OrderedLocusNames=STM1572;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 80-362.
RC STRAIN=SL1303;
RX PubMed=7926834; DOI=10.1016/0378-1119(94)90255-0;
RA Hongo E., Morimyo M., Mita K., Machida I., Hama-Inaba H., Tsuji H.,
RA Ichimura S., Noda Y.;
RT "The methyl viologen-resistance-encoding gene smvA of Salmonella
RT typhimurium.";
RL Gene 148:173-174(1994).
RN [3]
RP IDENTIFICATION AS OMPD.
RA Singh S.P., Miller S., Williams Y.U., Rudd K.E., Nikaido H.;
RL Unpublished observations (FEB-1996).
CC -!- FUNCTION: Forms pores that allow passive diffusion of small molecules
CC across the outer membrane. {ECO:0000250}.
CC -!- SUBUNIT: Homotrimer. {ECO:0000250}.
CC -!- INTERACTION:
CC P37592; Q8ZPI6: ydeI; NbExp=2; IntAct=EBI-2506775, EBI-2506763;
CC -!- SUBCELLULAR LOCATION: Cell outer membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the Gram-negative porin family. {ECO:0000305}.
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DR EMBL; AE006468; AAL20490.1; -; Genomic_DNA.
DR EMBL; D26057; BAA05056.1; -; Genomic_DNA.
DR RefSeq; NP_460531.1; NC_003197.2.
DR RefSeq; WP_000769035.1; NC_003197.2.
DR AlphaFoldDB; P37592; -.
DR SMR; P37592; -.
DR IntAct; P37592; 1.
DR STRING; 99287.STM1572; -.
DR PaxDb; 99287-STM1572; -.
DR GeneID; 1253090; -.
DR KEGG; stm:STM1572; -.
DR PATRIC; fig|99287.12.peg.1663; -.
DR HOGENOM; CLU_058202_0_0_6; -.
DR OMA; GENAEVW; -.
DR PhylomeDB; P37592; -.
DR BioCyc; SENT99287:STM1572-MONOMER; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:InterPro.
DR CDD; cd00342; gram_neg_porins; 1.
DR Gene3D; 2.40.160.10; Porin; 1.
DR InterPro; IPR033900; Gram_neg_porin_domain.
DR InterPro; IPR023614; Porin_dom_sf.
DR InterPro; IPR001897; Porin_gammaproteobac.
DR InterPro; IPR001702; Porin_Gram-ve.
DR InterPro; IPR013793; Porin_Gram-ve_CS.
DR PANTHER; PTHR34501:SF10; OUTER MEMBRANE PORIN PROTEIN NMPC-RELATED; 1.
DR PANTHER; PTHR34501; PROTEIN YDDL-RELATED; 1.
DR Pfam; PF00267; Porin_1; 1.
DR PRINTS; PR00183; ECOLIPORIN.
DR PRINTS; PR00182; ECOLNEIPORIN.
DR SUPFAM; SSF56935; Porins; 1.
DR PROSITE; PS00576; GRAM_NEG_PORIN; 1.
PE 1: Evidence at protein level;
KW Cell outer membrane; Ion transport; Membrane; Porin; Reference proteome;
KW Signal; Transmembrane; Transmembrane beta strand; Transport.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..362
FT /note="Outer membrane porin protein OmpD"
FT /id="PRO_0000025249"
FT CONFLICT 157
FT /note="N -> K (in Ref. 2; BAA05056)"
FT /evidence="ECO:0000305"
FT CONFLICT 258
FT /note="Missing (in Ref. 2; BAA05056)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 362 AA; 39680 MW; 9F68A9A7B948174C CRC64;
MKLKLVAVAV TSLLAAGVVN AAEVYNKDGN KLDLYGKVHA QHYFSDDNGS DGDKTYARLG
FKGETQINDQ LTGFGQWEYE FKGNRTESQG ADKDKTRLAF AGLKFADYGS FDYGRNYGVA
YDIGAWTDVL PEFGGDTWTQ TDVFMTGRTT GVATYRNTDF FGLVEGLNFA AQYQGKNDRD
GAYESNGDGF GLSATYEYEG FGVGAAYAKS DRTNNQVKAA SNLNAAGKNA EVWAAGLKYD
ANNIYLATTY SETLNMTTFG EDAAGDAFIA NKTQNFEAVA QYQFDFGLRP SIAYLKSKGK
NLGTYGDQDL VEYIDVGATY YFNKNMSTFV DYKINLLDDS DFTKAAKVST DNIVAVGLNY
QF
//
