ID OPPF_ECOLI Reviewed; 334 AA.
AC P77737; P76920;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 24-JAN-2024, entry version 160.
DE RecName: Full=Oligopeptide transport ATP-binding protein OppF;
GN Name=oppF; OrderedLocusNames=b1247, JW1239;
OS Escherichia coli (strain K12).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA Wada C., Yamamoto Y., Horiuchi T.;
RT "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 28.0-40.1 min region on the linkage map.";
RL DNA Res. 3:363-377(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC oligopeptides. Probably responsible for energy coupling to the
CC transport system.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR EMBL; U00096; AAC74329.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA14779.1; -; Genomic_DNA.
DR PIR; B64872; B64872.
DR RefSeq; NP_415763.1; NC_000913.3.
DR RefSeq; WP_000994906.1; NZ_CP064683.1.
DR AlphaFoldDB; P77737; -.
DR SMR; P77737; -.
DR BioGRID; 4260114; 420.
DR BioGRID; 850185; 2.
DR ComplexPortal; CPX-4343; Murein tripeptide ABC transporter complex.
DR ComplexPortal; CPX-4344; Oligopeptide ABC transporter complex.
DR DIP; DIP-10409N; -.
DR IntAct; P77737; 7.
DR STRING; 511145.b1247; -.
DR TCDB; 3.A.1.5.41; the atp-binding cassette (abc) superfamily.
DR jPOST; P77737; -.
DR PaxDb; 511145-b1247; -.
DR EnsemblBacteria; AAC74329; AAC74329; b1247.
DR GeneID; 945818; -.
DR KEGG; ecj:JW1239; -.
DR KEGG; eco:b1247; -.
DR PATRIC; fig|511145.12.peg.1297; -.
DR EchoBASE; EB0672; -.
DR eggNOG; COG4608; Bacteria.
DR HOGENOM; CLU_000604_1_23_6; -.
DR InParanoid; P77737; -.
DR PhylomeDB; P77737; -.
DR BioCyc; EcoCyc:OPPF-MONOMER; -.
DR BioCyc; MetaCyc:OPPF-MONOMER; -.
DR PRO; PR:P77737; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0055052; C:ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; NAS:ComplexPortal.
DR GO; GO:0016020; C:membrane; NAS:ComplexPortal.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0005524; F:ATP binding; ISM:EcoCyc.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140205; P:oligopeptide import across plasma membrane; NAS:ComplexPortal.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0140207; P:tripeptide import across plasma membrane; NAS:ComplexPortal.
DR CDD; cd03257; ABC_NikE_OppD_transporters; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013563; Oligopep_ABC_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01727; oligo_HPY; 1.
DR PANTHER; PTHR43776:SF7; D,D-DIPEPTIDE TRANSPORT ATP-BINDING PROTEIN DDPF-RELATED; 1.
DR PANTHER; PTHR43776; TRANSPORT ATP-BINDING PROTEIN; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF08352; oligo_HPY; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW Nucleotide-binding; Peptide transport; Protein transport;
KW Reference proteome; Transport.
FT CHAIN 1..334
FT /note="Oligopeptide transport ATP-binding protein OppF"
FT /id="PRO_0000092671"
FT DOMAIN 12..265
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 57..64
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 334 AA; 37198 MW; A3CD1309206A54EE CRC64;
MNAVTEGRKV LLEIADLKVH FEIKDGKQWF WQPPKTLKAV DGVTLRLYEG ETLGVVGESG
CGKSTFARAI IGLVKATDGH VAWLGKELLG MKPDEWRAVR SDIQMIFQDP LASLNPRMTI
GEIIAEPLRT YHPKMSRQEV RERVKAMMLK VGLLPNLINR YPHEFSGGQC QRIGIARALI
LEPKLIICDE PVSALDVSIQ AQVVNLLQQL QREMGLSLIF IAHDLAVVKH ISDRVLVMYL
GHAVELGTYD EVYHNPLHPY TRALMSAVPI PDPDLEKNKT IQLLEGELPS PINPPSGCVF
RTRCPIAGPE CAKTRPVLEG SFRHSVSCLK VDPL
//
