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Database: UniProt
Entry: P00219
LinkDB: P00219
Original site: P00219 
ID   FER_SULAC               Reviewed;         103 AA.
AC   P00219; Q4JBG2;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   30-AUG-2005, sequence version 2.
DT   16-JAN-2019, entry version 116.
DE   RecName: Full=Zinc-containing ferredoxin;
GN   Name=zfx; OrderedLocusNames=Saci_0456;
OS   Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 /
OS   NBRC 15157 / NCIMB 11770).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=330779;
RN   [1]
RP   PROTEIN SEQUENCE, AND METHYLATION AT LYS-29.
RC   STRAIN=ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770;
RX   PubMed=3926756;
RA   Minami Y., Wakabayashi S., Wada K., Matsubara H., Kerscher L.,
RA   Oesterhelt D.;
RT   "Amino acid sequence of a ferredoxin from thermoacidophilic
RT   archaebacterium, Sulfolobus acidocaldarius. Presence of an N6-
RT   monomethyllysine and phyletic consideration of archaebacteria.";
RL   J. Biochem. 97:745-753(1985).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770;
RX   PubMed=15995215; DOI=10.1128/JB.187.14.4992-4999.2005;
RA   Chen L., Bruegger K., Skovgaard M., Redder P., She Q., Torarinsson E.,
RA   Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A.;
RT   "The genome of Sulfolobus acidocaldarius, a model organism of the
RT   Crenarchaeota.";
RL   J. Bacteriol. 187:4992-4999(2005).
RN   [3]
RP   PROTEIN SEQUENCE OF 1-30, AND PRESENCE OF A 3FE-4S AND A 4FE-4S
RP   CLUSTER.
RC   STRAIN=ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770;
RX   PubMed=8521862; DOI=10.1111/j.1432-1033.1995.937_3.x;
RA   Breton J.L., Duff J.L., Butt J.N., Armstrong F.A., George S.J.,
RA   Petillot Y., Forest E., Schafer G., Thomson A.J.;
RT   "Identification of the iron-sulfur clusters in a ferredoxin from the
RT   archaeon Sulfolobus acidocaldarius. Evidence for a reduced [3Fe-4S]
RT   cluster with pH-dependent electronic properties.";
RL   Eur. J. Biochem. 233:937-946(1995).
CC   -!- FUNCTION: Ferredoxins are iron-sulfur proteins that transfer
CC       electrons in a wide variety of metabolic reactions.
CC   -!- COFACTOR:
CC       Name=[3Fe-4S] cluster; Xref=ChEBI:CHEBI:21137;
CC         Evidence={ECO:0000250};
CC       Note=Binds 1 [3Fe-4S] cluster. {ECO:0000250};
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000250};
CC       Note=Binds 1 [4Fe-4S] cluster. {ECO:0000250};
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250};
CC       Note=Binds 1 zinc ion. {ECO:0000250};
DR   EMBL; CP000077; AAY79867.1; -; Genomic_DNA.
DR   PIR; A00223; FEUC.
DR   ProteinModelPortal; P00219; -.
DR   SMR; P00219; -.
DR   STRING; 330779.Saci_0456; -.
DR   iPTMnet; P00219; -.
DR   EnsemblBacteria; AAY79867; AAY79867; Saci_0456.
DR   KEGG; sai:Saci_0456; -.
DR   PATRIC; fig|330779.12.peg.454; -.
DR   eggNOG; arCOG04548; Archaea.
DR   eggNOG; COG1146; LUCA.
DR   HOGENOM; HOG000044616; -.
DR   OMA; EWVDTPG; -.
DR   Proteomes; UP000001018; Chromosome.
DR   GO; GO:0051538; F:3 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR009157; Fd_Zn-bd.
DR   Pfam; PF13187; Fer4_9; 1.
DR   PIRSF; PIRSF000068; Zn_Fdx_Sulfol; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 2.
PE   1: Evidence at protein level;
KW   3Fe-4S; 4Fe-4S; Complete proteome; Direct protein sequencing;
KW   Electron transport; Iron; Iron-sulfur; Metal-binding; Methylation;
KW   Reference proteome; Repeat; Transport; Zinc.
FT   CHAIN         1    103       Zinc-containing ferredoxin.
FT                                /FTId=PRO_0000159177.
FT   DOMAIN       35     65       4Fe-4S ferredoxin-type 1.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00711}.
FT   DOMAIN       74    103       4Fe-4S ferredoxin-type 2.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00711}.
FT   REGION        1     36       N-terminal extension.
FT   METAL        19     19       Zinc. {ECO:0000250}.
FT   METAL        34     34       Zinc. {ECO:0000250}.
FT   METAL        45     45       Iron-sulfur 1 (3Fe-4S). {ECO:0000250}.
FT   METAL        51     51       Iron-sulfur 1 (3Fe-4S). {ECO:0000250}.
FT   METAL        55     55       Iron-sulfur 2 (4Fe-4S). {ECO:0000250}.
FT   METAL        76     76       Zinc. {ECO:0000250}.
FT   METAL        83     83       Iron-sulfur 2 (4Fe-4S). {ECO:0000250}.
FT   METAL        86     86       Iron-sulfur 2 (4Fe-4S). {ECO:0000250}.
FT   METAL        89     89       Iron-sulfur 2 (4Fe-4S). {ECO:0000250}.
FT   METAL        93     93       Iron-sulfur 1 (3Fe-4S). {ECO:0000250}.
FT   MOD_RES      29     29       N6-methyllysine.
FT                                {ECO:0000269|PubMed:3926756}.
FT   CONFLICT      9      9       S -> H (in Ref. 1; AA sequence).
FT                                {ECO:0000305}.
FT   CONFLICT     16     16       H -> S (in Ref. 1; AA sequence).
FT                                {ECO:0000305}.
FT   CONFLICT     80     80       E -> Q (in Ref. 1; AA sequence).
FT                                {ECO:0000305}.
SQ   SEQUENCE   103 AA;  10893 MW;  6AD0900817C1A4D3 CRC64;
     GIDPNYRTSK PVVGDHSGHK IYGPVESPKV LGVHGTIVGV DFDLCIADGS CITACPVNVF
     QWYETPGHPA SEKKADPVNE QACIFCMACV NVCPVAAIDV KPP
//
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