ID HV2B_RABIT Reviewed; 117 AA.
AC P01828;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=Ig heavy chain V-A2 region K-25;
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986;
RN [1]
RP PROTEIN SEQUENCE, AND PYROGLUTAMATE FORMATION AT GLN-1.
RX PubMed=241319; DOI=10.1042/bj1470235;
RA Jaton J.-C.;
RT "Comparison of the amino acid sequences of the variable domains of two
RT homogeneous rabbit antibodies to type III pneumococcal polysaccharide.";
RL Biochem. J. 147:235-247(1975).
CC -!- MISCELLANEOUS: This chain was obtained from antibody to type III
CC pneumococci and was isolated from the serum of a single rabbit.
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DR PIR; A02104; GARB2K.
DR InParanoid; P01828; -.
DR Proteomes; UP000001811; Unplaced.
DR GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR23266:SF269; IG HEAVY CHAIN V REGION MC101-RELATED; 1.
DR PANTHER; PTHR23266; IMMUNOGLOBULIN HEAVY CHAIN; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 1: Evidence at protein level;
KW Adaptive immunity; Direct protein sequencing; Disulfide bond; Immunity;
KW Immunoglobulin; Pyrrolidone carboxylic acid; Reference proteome.
FT CHAIN 1..>117
FT /note="Ig heavy chain V-A2 region K-25"
FT /id="PRO_0000059937"
FT DOMAIN 1..106
FT /note="Ig-like"
FT MOD_RES 1
FT /note="Pyrrolidone carboxylic acid"
FT /evidence="ECO:0000269|PubMed:241319"
FT DISULFID 21..91
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00114,
FT ECO:0000269|PubMed:241319"
FT NON_TER 117
SQ SEQUENCE 117 AA; 12580 MW; 28DD87FDB7AEE9B8 CRC64;
QSVKESEGGL FKPTDTLTLT CTVSGFSLSG YDMSWVRQAP GKGLEWIGVI YASGSTYYAT
WAKSRSTITR TSBTVBLMDS LTAQDTATYF CARGHTGLSY LKSSVDVWGP GTLVTVS
//
