ID ADCC_STRR6 Reviewed; 234 AA.
AC P0A2U7; O87862;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE RecName: Full=Zinc transport system ATP-binding protein AdcC;
GN Name=adcC; OrderedLocusNames=spr1977;
OS Streptococcus pneumoniae (strain ATCC BAA-255 / R6).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=171101;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9765793; DOI=10.1016/s0923-2508(97)87643-7;
RA Dintilhac A., Claverys J.-P.;
RT "The adc locus, which affects competence for genetic transformation in
RT Streptococcus pneumoniae, encodes an ABC transporter with a putative
RT lipoprotein homologous to a family of streptococcal adhesins.";
RL Res. Microbiol. 148:119-131(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-255 / R6;
RX PubMed=11544234; DOI=10.1128/jb.183.19.5709-5717.2001;
RA Hoskins J., Alborn W.E. Jr., Arnold J., Blaszczak L.C., Burgett S.,
RA DeHoff B.S., Estrem S.T., Fritz L., Fu D.-J., Fuller W., Geringer C.,
RA Gilmour R., Glass J.S., Khoja H., Kraft A.R., Lagace R.E., LeBlanc D.J.,
RA Lee L.N., Lefkowitz E.J., Lu J., Matsushima P., McAhren S.M., McHenney M.,
RA McLeaster K., Mundy C.W., Nicas T.I., Norris F.H., O'Gara M., Peery R.B.,
RA Robertson G.T., Rockey P., Sun P.-M., Winkler M.E., Yang Y.,
RA Young-Bellido M., Zhao G., Zook C.A., Baltz R.H., Jaskunas S.R.,
RA Rosteck P.R. Jr., Skatrud P.L., Glass J.I.;
RT "Genome of the bacterium Streptococcus pneumoniae strain R6.";
RL J. Bacteriol. 183:5709-5717(2001).
CC -!- FUNCTION: Part of the ATP-driven transport system AdcABC for zinc.
CC Required for transformability (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR EMBL; Z71552; CAA96186.1; -; Genomic_DNA.
DR EMBL; AE007317; AAL00779.1; -; Genomic_DNA.
DR PIR; F98118; F98118.
DR PIR; T46754; T46754.
DR RefSeq; NP_359568.1; NC_003098.1.
DR RefSeq; WP_001269474.1; NC_003098.1.
DR AlphaFoldDB; P0A2U7; -.
DR SMR; P0A2U7; -.
DR STRING; 171101.spr1977; -.
DR KEGG; spr:spr1977; -.
DR PATRIC; fig|171101.6.peg.2140; -.
DR eggNOG; COG1121; Bacteria.
DR HOGENOM; CLU_000604_1_11_9; -.
DR Proteomes; UP000000586; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:UniProtKB-KW.
DR GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
DR CDD; cd03235; ABC_Metallic_Cations; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR42734; METAL TRANSPORT SYSTEM ATP-BINDING PROTEIN TM_0124-RELATED; 1.
DR PANTHER; PTHR42734:SF4; ZINC TRANSPORT SYSTEM ATP-BINDING PROTEIN ADCC; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Competence; Ion transport; Nucleotide-binding;
KW Reference proteome; Transport; Zinc; Zinc transport.
FT CHAIN 1..234
FT /note="Zinc transport system ATP-binding protein AdcC"
FT /id="PRO_0000091923"
FT DOMAIN 4..234
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 36..43
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 234 AA; 26542 MW; 2AF782EF93D5C1A0 CRC64;
MRYITVEDLS FYYDKEPVLE HINYCVDSGE FVTLTGENGA AKTTLIKASL GILQPRIGKV
AISKTNTQGK KLRIAYLPQQ IASFNAGFPS TVYEFVKSGR YPRKGWFRRL NAHDEEHIKA
SLDSVGMWEH RDKRLGSLSG GQKQRAVIAR MFASDPDVFI LDEPTTGMDA GSKNEFYELM
HHSAHHHGKA VLMITHDPEE VKDYADRNIH LVRNQDSPWR CFNVHENGQE VGHA
//
