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Database: UniProt
Entry: P0A415
LinkDB: P0A415
Original site: P0A415 
ID   PSAC_THEEB              Reviewed;          81 AA.
AC   P0A415; P18083; P20451;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   10-APR-2019, entry version 97.
DE   RecName: Full=Photosystem I iron-sulfur center;
DE            EC=1.97.1.12;
DE   AltName: Full=9 kDa polypeptide;
DE   AltName: Full=PSI-C;
DE   AltName: Full=Photosystem I subunit VII;
DE   AltName: Full=PsaC;
GN   Name=psaC; OrderedLocusNames=tsl1013;
OS   Thermosynechococcus elongatus (strain BP-1).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae;
OC   Thermosynechococcus.
OX   NCBI_TaxID=197221;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BP-1;
RX   PubMed=12240834; DOI=10.1093/dnares/9.4.123;
RA   Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S.,
RA   Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y.,
RA   Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N.,
RA   Shimpo S., Sugimoto M., Takeuchi C., Yamada M., Tabata S.;
RT   "Complete genome structure of the thermophilic cyanobacterium
RT   Thermosynechococcus elongatus BP-1.";
RL   DNA Res. 9:123-130(2002).
RN   [2]
RP   REVIEW.
RX   PubMed=11687205; DOI=10.1016/S0005-2728(01)00195-5;
RA   Fromme P., Jordan P., Krauss N.;
RT   "Structure of photosystem I.";
RL   Biochim. Biophys. Acta 1507:5-31(2001).
RN   [3]
RP   X-RAY CRYSTALLOGRAPHY (4.0 ANGSTROMS), SUBUNIT, AND SUBCELLULAR
RP   LOCATION.
RX   PubMed=8901876; DOI=10.1038/nsb1196-965;
RA   Krauss N., Schubert W.-D., Klukas O., Fromme P., Witt H.T.,
RA   Saenger W.;
RT   "Photosystem I at 4-A resolution represents the first structural model
RT   of a joint photosynthetic reaction centre and core antenna system.";
RL   Nat. Struct. Biol. 3:965-973(1996).
RN   [4]
RP   X-RAY CRYSTALLOGRAPHY (4.0 ANGSTROMS), SUBUNIT, AND SUBCELLULAR
RP   LOCATION.
RX   PubMed=10066799; DOI=10.1074/jbc.274.11.7351;
RA   Klukas O., Schubert W.-D., Jordan P., Krauss N., Fromme P., Witt H.T.,
RA   Saenger W.;
RT   "Photosystem I, an improved model of the stromal subunits PsaC, PsaD,
RT   and PsaE.";
RL   J. Biol. Chem. 274:7351-7360(1999).
RN   [5]
RP   X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 2-81 IN COMPLEX WITH 4FE-4S
RP   CLUSTER, COFACTOR, SUBUNIT, AND SUBCELLULAR LOCATION.
RX   PubMed=11418848; DOI=10.1038/35082000;
RA   Jordan P., Fromme P., Witt H.T., Klukas O., Saenger W., Krauss N.;
RT   "Three-dimensional structure of cyanobacterial photosystem I at 2.5 A
RT   resolution.";
RL   Nature 411:909-917(2001).
CC   -!- FUNCTION: Apoprotein for the two 4Fe-4S centers FA and FB of
CC       photosystem I (PSI); essential for photochemical activity. FB is
CC       the terminal electron acceptor of PSI, donating electrons to
CC       ferredoxin. The C-terminus interacts with PsaA/B/D and helps
CC       assemble the protein into the PSI complex. Required for binding of
CC       PsaD and PsaE to PSI. PSI is a plastocyanin/cytochrome c6-
CC       ferredoxin oxidoreductase, converting photonic excitation into a
CC       charge separation, which transfers an electron from the donor P700
CC       chlorophyll pair to the spectroscopically characterized acceptors
CC       A0, A1, FX, FA and FB in turn.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=hnu + oxidized [2Fe-2S]-[ferredoxin] + reduced
CC         [plastocyanin] = oxidized [plastocyanin] + reduced [2Fe-2S]-
CC         [ferredoxin]; Xref=Rhea:RHEA:30407, Rhea:RHEA-COMP:10000,
CC         Rhea:RHEA-COMP:10001, Rhea:RHEA-COMP:10039, Rhea:RHEA-
CC         COMP:10040, ChEBI:CHEBI:29036, ChEBI:CHEBI:30212,
CC         ChEBI:CHEBI:33737, ChEBI:CHEBI:33738, ChEBI:CHEBI:49552;
CC         EC=1.97.1.12;
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000269|PubMed:11418848};
CC       Note=Binds 2 [4Fe-4S] clusters. Cluster 2 is most probably the
CC       spectroscopically characterized electron acceptor FA and cluster 1
CC       is most probably FB. {ECO:0000305|PubMed:11418848};
CC   -!- SUBUNIT: The cyanobacterial PSI reaction center is composed of one
CC       copy each of PsaA,B,C,D,E,F,I,J,K,L,M and X, and forms trimeric
CC       complexes. {ECO:0000269|PubMed:10066799,
CC       ECO:0000269|PubMed:11418848, ECO:0000269|PubMed:8901876}.
CC   -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane
CC       {ECO:0000269|PubMed:10066799, ECO:0000269|PubMed:11418848,
CC       ECO:0000269|PubMed:8901876}; Peripheral membrane protein
CC       {ECO:0000269|PubMed:11418848}; Cytoplasmic side
CC       {ECO:0000269|PubMed:11418848}.
DR   EMBL; BA000039; BAC08565.1; -; Genomic_DNA.
DR   RefSeq; NP_681803.1; NC_004113.1.
DR   RefSeq; WP_011056855.1; NC_004113.1.
DR   PDB; 1C51; X-ray; 4.0 A; -.
DR   PDB; 1JB0; X-ray; 2.50 A; C=2-81.
DR   PDB; 2PPS; X-ray; 4.0 A; -.
DR   PDB; 3PCQ; X-ray; 8.98 A; C=2-81.
DR   PDB; 4FE1; X-ray; 4.92 A; C=2-81.
DR   PDB; 5ZF0; X-ray; 4.20 A; C1/C2/C3/C4/C5/C6=2-81.
DR   PDBsum; 1C51; -.
DR   PDBsum; 1JB0; -.
DR   PDBsum; 2PPS; -.
DR   PDBsum; 3PCQ; -.
DR   PDBsum; 4FE1; -.
DR   PDBsum; 5ZF0; -.
DR   ProteinModelPortal; P0A415; -.
DR   SMR; P0A415; -.
DR   STRING; 197221.22294736; -.
DR   EnsemblBacteria; BAC08565; BAC08565; BAC08565.
DR   GeneID; 1011306; -.
DR   KEGG; tel:tsl1013; -.
DR   PATRIC; fig|197221.4.peg.1063; -.
DR   eggNOG; ENOG4108Z6M; Bacteria.
DR   eggNOG; COG1145; LUCA.
DR   HOGENOM; HOG000230505; -.
DR   KO; K02691; -.
DR   OMA; AHTVKIY; -.
DR   OrthoDB; 1873445at2; -.
DR   BioCyc; TELO197221:G1G3I-1031-MONOMER; -.
DR   EvolutionaryTrace; P0A415; -.
DR   Proteomes; UP000000440; Chromosome.
DR   GO; GO:0009522; C:photosystem I; IEA:UniProtKB-KW.
DR   GO; GO:0042651; C:thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0009055; F:electron transfer activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009773; P:photosynthetic electron transport in photosystem I; IEA:InterPro.
DR   HAMAP; MF_01303; PSI_PsaC; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR017491; PSI_PsaC.
DR   Pfam; PF12838; Fer4_7; 1.
DR   TIGRFAMs; TIGR03048; PS_I_psaC; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 2.
DR   PROSITE; PS51379; 4FE4S_FER_2; 2.
PE   1: Evidence at protein level;
KW   3D-structure; 4Fe-4S; Complete proteome; Electron transport; Iron;
KW   Iron-sulfur; Membrane; Metal-binding; Oxidoreductase; Photosynthesis;
KW   Photosystem I; Reference proteome; Repeat; Thylakoid; Transport.
FT   INIT_MET      1      1       Removed. {ECO:0000250}.
FT   CHAIN         2     81       Photosystem I iron-sulfur center.
FT                                /FTId=PRO_0000062018.
FT   DOMAIN        2     31       4Fe-4S ferredoxin-type 1.
FT   DOMAIN       37     68       4Fe-4S ferredoxin-type 2.
FT   METAL        11     11       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000269|PubMed:11418848}.
FT   METAL        14     14       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000269|PubMed:11418848}.
FT   METAL        17     17       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000269|PubMed:11418848}.
FT   METAL        21     21       Iron-sulfur 2 (4Fe-4S).
FT                                {ECO:0000269|PubMed:11418848}.
FT   METAL        48     48       Iron-sulfur 2 (4Fe-4S).
FT                                {ECO:0000269|PubMed:11418848}.
FT   METAL        51     51       Iron-sulfur 2 (4Fe-4S).
FT                                {ECO:0000269|PubMed:11418848}.
FT   METAL        54     54       Iron-sulfur 2 (4Fe-4S).
FT                                {ECO:0000269|PubMed:11418848}.
FT   METAL        58     58       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000269|PubMed:11418848}.
FT   STRAND        4      8       {ECO:0000244|PDB:1JB0}.
FT   HELIX        16     20       {ECO:0000244|PDB:1JB0}.
FT   STRAND       27     30       {ECO:0000244|PDB:1JB0}.
FT   STRAND       32     34       {ECO:0000244|PDB:1JB0}.
FT   STRAND       37     41       {ECO:0000244|PDB:1JB0}.
FT   HELIX        45     47       {ECO:0000244|PDB:1JB0}.
FT   HELIX        53     57       {ECO:0000244|PDB:1JB0}.
FT   STRAND       60     62       {ECO:0000244|PDB:1JB0}.
FT   STRAND       64     68       {ECO:0000244|PDB:1JB0}.
FT   TURN         74     78       {ECO:0000244|PDB:1JB0}.
SQ   SEQUENCE   81 AA;  8800 MW;  ED5362F4D6E48F36 CRC64;
     MAHTVKIYDT CIGCTQCVRA CPTDVLEMVP WDGCKAGQIA SSPRTEDCVG CKRCETACPT
     DFLSIRVYLG AETTRSMGLA Y
//
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