ID FLGH_ECOLI Reviewed; 232 AA.
AC P0A6S0; P75940; Q9R7P0;
DT 29-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 29-MAR-2005, sequence version 1.
DT 27-MAR-2024, entry version 118.
DE RecName: Full=Flagellar L-ring protein;
DE AltName: Full=Basal body L-ring protein;
DE Flags: Precursor;
GN Name=flgH; Synonyms=fla FVIII, flaY; OrderedLocusNames=b1079, JW5153;
OS Escherichia coli (strain K12).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- FUNCTION: Assembles around the rod to form the L-ring and probably
CC protects the motor/basal body from shearing forces during rotation.
CC {ECO:0000250}.
CC -!- SUBUNIT: The basal body constitutes a major portion of the flagellar
CC organelle and consists of four rings (L,P,S, and M) mounted on a
CC central rod. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Lipid-anchor
CC {ECO:0000250}. Bacterial flagellum basal body {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the FlgH family. {ECO:0000305}.
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DR EMBL; U00096; AAC74163.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA35888.2; -; Genomic_DNA.
DR PIR; D64851; D64851.
DR RefSeq; NP_415597.1; NC_000913.3.
DR RefSeq; WP_001295442.1; NZ_STEB01000016.1.
DR AlphaFoldDB; P0A6S0; -.
DR SMR; P0A6S0; -.
DR BioGRID; 4261033; 6.
DR IntAct; P0A6S0; 13.
DR STRING; 511145.b1079; -.
DR jPOST; P0A6S0; -.
DR PaxDb; 511145-b1079; -.
DR EnsemblBacteria; AAC74163; AAC74163; b1079.
DR GeneID; 75203666; -.
DR GeneID; 946996; -.
DR KEGG; ecj:JW5153; -.
DR KEGG; eco:b1079; -.
DR PATRIC; fig|1411691.4.peg.1189; -.
DR EchoBASE; EB4161; -.
DR eggNOG; COG2063; Bacteria.
DR HOGENOM; CLU_069313_0_0_6; -.
DR InParanoid; P0A6S0; -.
DR OMA; WFDRFFL; -.
DR OrthoDB; 9789463at2; -.
DR PhylomeDB; P0A6S0; -.
DR BioCyc; EcoCyc:FLGH-FLAGELLAR-L-RING; -.
DR PRO; PR:P0A6S0; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0009427; C:bacterial-type flagellum basal body, distal rod, L ring; IEA:InterPro.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:InterPro.
DR GO; GO:0006970; P:response to osmotic stress; IMP:EcoCyc.
DR HAMAP; MF_00415; FlgH; 1.
DR InterPro; IPR000527; Flag_Lring.
DR PANTHER; PTHR34933; FLAGELLAR L-RING PROTEIN; 1.
DR PANTHER; PTHR34933:SF3; FLAGELLAR L-RING PROTEIN; 1.
DR Pfam; PF02107; FlgH; 1.
DR PRINTS; PR01008; FLGLRINGFLGH.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum; Cell outer membrane; Lipoprotein; Membrane; Palmitate;
KW Reference proteome; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..232
FT /note="Flagellar L-ring protein"
FT /id="PRO_0000009443"
FT LIPID 22
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255"
FT LIPID 22
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 232 AA; 24615 MW; 862560170E6F63B7 CRC64;
MQKNAAHTYA ISSLLVLSLT GCAWIPSTPL VQGATSAQPV PGPTPVANGS IFQSAQPINY
GYQPLFEDRR PRNIGDTLTI VLQENVSASK SSSANASRDG KTNFGFDTVP RYLQGLFGNA
RADVEASGGN TFNGKGGANA SNTFSGTLTV TVDQVLVNGN LHVVGEKQIA INQGTEFIRF
SGVVNPRTIS GSNTVPSTQV ADARIEYVGN GYINEAQNMG WLQRFFLNLS PM
//
