ID SLYB_ECOLI Reviewed; 155 AA.
AC P0A905; P55741; P76183;
DT 19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2005, sequence version 1.
DT 24-JAN-2024, entry version 116.
DE RecName: Full=Outer membrane lipoprotein SlyB;
DE Flags: Precursor;
GN Name=slyB; OrderedLocusNames=b1641, JW1633;
OS Escherichia coli (strain K12).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8544813; DOI=10.1007/bf00290573;
RA Ludwig A., Tengel C., Bauer S., Bubert A., Benz R., Mollenkopf H.-J.,
RA Goebel W.;
RT "SlyA, a regulatory protein from Salmonella typhimurium, induces a
RT haemolytic and pore-forming protein in Escherichia coli.";
RL Mol. Gen. Genet. 249:474-486(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA Wada C., Yamamoto Y., Horiuchi T.;
RT "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 28.0-40.1 min region on the linkage map.";
RL DNA Res. 3:363-377(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP SEQUENCE REVISION TO 98.
RX PubMed=16397293; DOI=10.1093/nar/gkj405;
RA Riley M., Abe T., Arnaud M.B., Berlyn M.K.B., Blattner F.R.,
RA Chaudhuri R.R., Glasner J.D., Horiuchi T., Keseler I.M., Kosuge T.,
RA Mori H., Perna N.T., Plunkett G. III, Rudd K.E., Serres M.H., Thomas G.H.,
RA Thomson N.R., Wishart D., Wanner B.L.;
RT "Escherichia coli K-12: a cooperatively developed annotation snapshot
RT -- 2005.";
RL Nucleic Acids Res. 34:1-9(2006).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [6]
RP INDUCTION.
RC STRAIN=K12;
RX PubMed=12813061; DOI=10.1128/jb.185.13.3696-3702.2003;
RA Minagawa S., Ogasawara H., Kato A., Yamamoto K., Eguchi Y., Oshima T.,
RA Mori H., Ishihama A., Utsumi R.;
RT "Identification and molecular characterization of the Mg2+ stimulon of
RT Escherichia coli.";
RL J. Bacteriol. 185:3696-3702(2003).
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305}; Lipid-anchor
CC {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC -!- INDUCTION: Induced by low extracellular levels of magnesium via the
CC PhoQ/PhoP two-component regulatory system.
CC {ECO:0000269|PubMed:12813061}.
CC -!- SIMILARITY: Belongs to the Pcp/SlyB lipoprotein family. {ECO:0000305}.
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DR EMBL; U00096; AAT48133.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA15402.1; -; Genomic_DNA.
DR PIR; C64921; C64921.
DR RefSeq; WP_000597196.1; NZ_STEB01000003.1.
DR RefSeq; YP_025304.1; NC_000913.3.
DR AlphaFoldDB; P0A905; -.
DR SMR; P0A905; -.
DR BioGRID; 4263490; 212.
DR BioGRID; 851142; 1.
DR IntAct; P0A905; 4.
DR STRING; 511145.b1641; -.
DR jPOST; P0A905; -.
DR PaxDb; 511145-b1641; -.
DR EnsemblBacteria; AAT48133; AAT48133; b1641.
DR GeneID; 75204486; -.
DR GeneID; 946801; -.
DR KEGG; ecj:JW1633; -.
DR KEGG; eco:b1641; -.
DR PATRIC; fig|1411691.4.peg.619; -.
DR EchoBASE; EB3185; -.
DR eggNOG; COG3133; Bacteria.
DR HOGENOM; CLU_090265_3_1_6; -.
DR InParanoid; P0A905; -.
DR OMA; GCAYNSS; -.
DR OrthoDB; 5298161at2; -.
DR PhylomeDB; P0A905; -.
DR BioCyc; EcoCyc:G6881-MONOMER; -.
DR PRO; PR:P0A905; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IDA:EcoCyc.
DR InterPro; IPR008816; Gly_zipper_2TM_dom.
DR PANTHER; PTHR35603; -; 1.
DR PANTHER; PTHR35603:SF1; OUTER MEMBRANE LIPOPROTEIN SLYB; 1.
DR Pfam; PF05433; Rick_17kDa_Anti; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 2: Evidence at transcript level;
KW Cell outer membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW Signal.
FT SIGNAL 1..17
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT CHAIN 18..155
FT /note="Outer membrane lipoprotein SlyB"
FT /id="PRO_0000018161"
FT LIPID 18
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT LIPID 18
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ SEQUENCE 155 AA; 15602 MW; 543EB8A4069A5FA3 CRC64;
MIKRVLVVSM VGLSLVGCVN NDTLSGDVYT ASEAKQVQNV SYGTIVNVRP VQIQGGDDSN
VIGAIGGAVL GGFLGNTVGG GTGRSLATAA GAVAGGVAGQ GVQSAMNKTQ GVELEIRKDD
GNTIMVVQKQ GNTRFSPGQR VVLASNGSQV TVSPR
//
