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Database: UniProt
Entry: P0ABE0
LinkDB: P0ABE0
Original site: P0ABE0 
ID   BCCP_ECO57              Reviewed;         156 AA.
AC   P0ABE0; P02905;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2005, sequence version 1.
DT   10-APR-2019, entry version 79.
DE   RecName: Full=Biotin carboxyl carrier protein of acetyl-CoA carboxylase;
DE            Short=BCCP;
GN   Name=accB; OrderedLocusNames=Z4615, ECs4127;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: This protein is a component of the acetyl coenzyme A
CC       carboxylase complex; first, biotin carboxylase catalyzes the
CC       carboxylation of the carrier protein and then the transcarboxylase
CC       transfers the carboxyl group to form malonyl-CoA. {ECO:0000250}.
CC   -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
DR   EMBL; AE005174; AAG58383.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB37550.1; -; Genomic_DNA.
DR   PIR; C85990; C85990.
DR   PIR; G91144; G91144.
DR   RefSeq; NP_312154.1; NC_002695.1.
DR   RefSeq; WP_000354622.1; NZ_RICC01000007.1.
DR   DisProt; DP00415; -.
DR   ProteinModelPortal; P0ABE0; -.
DR   SMR; P0ABE0; -.
DR   STRING; 155864.EDL933_4477; -.
DR   PRIDE; P0ABE0; -.
DR   EnsemblBacteria; AAG58383; AAG58383; Z4615.
DR   EnsemblBacteria; BAB37550; BAB37550; BAB37550.
DR   GeneID; 916025; -.
DR   KEGG; ece:Z4615; -.
DR   KEGG; ecs:ECs4127; -.
DR   PATRIC; fig|386585.9.peg.4310; -.
DR   eggNOG; ENOG4105KM4; Bacteria.
DR   eggNOG; COG0511; LUCA.
DR   HOGENOM; HOG000008875; -.
DR   KO; K02160; -.
DR   UniPathway; UPA00094; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0009317; C:acetyl-CoA carboxylase complex; IEA:InterPro.
DR   GO; GO:0003989; F:acetyl-CoA carboxylase activity; IEA:InterPro.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR001249; AcCoA_biotinCC.
DR   InterPro; IPR001882; Biotin_BS.
DR   InterPro; IPR000089; Biotin_lipoyl.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   Pfam; PF00364; Biotin_lipoyl; 1.
DR   PRINTS; PR01071; ACOABIOTINCC.
DR   SUPFAM; SSF51230; SSF51230; 1.
DR   TIGRFAMs; TIGR00531; BCCP; 1.
DR   PROSITE; PS00188; BIOTIN; 1.
DR   PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
PE   3: Inferred from homology;
KW   Biotin; Complete proteome; Fatty acid biosynthesis;
KW   Fatty acid metabolism; Lipid biosynthesis; Lipid metabolism;
KW   Reference proteome.
FT   CHAIN         1    156       Biotin carboxyl carrier protein of
FT                                acetyl-CoA carboxylase.
FT                                /FTId=PRO_0000146806.
FT   DOMAIN       73    156       Biotinyl-binding. {ECO:0000255|PROSITE-
FT                                ProRule:PRU01066}.
FT   MOD_RES     122    122       N6-biotinyllysine. {ECO:0000250,
FT                                ECO:0000255|PROSITE-ProRule:PRU01066}.
SQ   SEQUENCE   156 AA;  16687 MW;  05FFDCB912A683A3 CRC64;
     MDIRKIKKLI ELVEESGISE LEISEGEESV RISRAAPAAS FPVMQQAYAA PMMQQPAQSN
     AAAPATVPSM EAPAAAEISG HIVRSPMVGT FYRTPSPDAK AFIEVGQKVN VGDTLCIVEA
     MKMMNQIEAD KSGTVKAILV ESGQPVEFDE PLVVIE
//
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