ID ECNB_ECO57 Reviewed; 48 AA.
AC P0ADB9; P56549;
DT 06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 06-DEC-2005, sequence version 1.
DT 24-JAN-2024, entry version 83.
DE RecName: Full=Entericidin B;
DE Flags: Precursor;
GN Name=ecnB; OrderedLocusNames=Z5754, ECs5128.2;
OS Escherichia coli O157:H7.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83334;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX PubMed=11206551; DOI=10.1038/35054089;
RA Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA Blattner F.R.;
RT "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL Nature 409:529-533(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
CC -!- FUNCTION: Plays a role in the bacteriolysis. Is activated under
CC conditions of high osmolarity by the factor sigma S. Entericidin A
CC functions as an antidote (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC -!- SIMILARITY: Belongs to the EcnA/EcnB lipoprotein family. {ECO:0000305}.
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DR EMBL; AE005174; AAG59348.1; -; Genomic_DNA.
DR EMBL; BA000007; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; H86110; H86110.
DR RefSeq; WP_000239596.1; NZ_VOAI01000008.1.
DR AlphaFoldDB; P0ADB9; -.
DR STRING; 155864.Z5754; -.
DR GeneID; 83579156; -.
DR KEGG; ece:Z5754; -.
DR PATRIC; fig|83334.175.peg.5688; -.
DR eggNOG; COG5510; Bacteria.
DR Proteomes; UP000000558; Chromosome.
DR Proteomes; UP000002519; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009636; P:response to toxic substance; IEA:InterPro.
DR InterPro; IPR012556; Entericidin.
DR Pfam; PF08085; Entericidin; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT PEPTIDE 22..48
FT /note="Entericidin B"
FT /id="PRO_0000043192"
FT LIPID 22
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000305"
FT LIPID 22
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000305"
SQ SEQUENCE 48 AA; 4810 MW; 9814A908CA6A70CC CRC64;
MVKKTIAAIF SVLVLSTVLT ACNTTRGVGE DISDGGNAIS GAATKAQQ
//
