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Database: UniProt
Entry: P0CR43
LinkDB: P0CR43
Original site: P0CR43 
ID   SET5_CRYNB              Reviewed;         449 AA.
AC   P0CR43; Q55Y21; Q5KLW8;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   10-APR-2019, entry version 21.
DE   RecName: Full=Potential protein lysine methyltransferase SET5;
DE            EC=2.1.1.-;
DE   AltName: Full=SET domain-containing protein 5;
GN   Name=SET5; OrderedLocusNames=CNBB1930;
OS   Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
OS   (Filobasidiella neoformans).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina;
OC   Tremellomycetes; Tremellales; Cryptococcaceae; Cryptococcus;
OC   Cryptococcus neoformans species complex.
OX   NCBI_TaxID=283643;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B-3501A;
RX   PubMed=15653466; DOI=10.1126/science.1103773;
RA   Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA   Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA   Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J.,
RA   D'Souza C.A., Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J.,
RA   Huang J.C., Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I.,
RA   Kwon-Chung K.J., Lengeler K.B., Maiti R., Marra M.A., Marra R.E.,
RA   Mathewson C.A., Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L.,
RA   Schein J.E., Shvartsbeyn A., Shin H., Shumway M., Specht C.A.,
RA   Suh B.B., Tenney A., Utterback T.R., Wickes B.L., Wortman J.R.,
RA   Wye N.H., Kronstad J.W., Lodge J.K., Heitman J., Davis R.W.,
RA   Fraser C.M., Hyman R.W.;
RT   "The genome of the basidiomycetous yeast and human pathogen
RT   Cryptococcus neoformans.";
RL   Science 307:1321-1324(2005).
CC   -!- FUNCTION: Putative protein lysine methyltransferase.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the class V-like SAM-binding
CC       methyltransferase superfamily. Histone-lysine methyltransferase
CC       family. SET5 subfamily. {ECO:0000255|PROSITE-ProRule:PRU00190}.
DR   EMBL; AAEY01000007; EAL22745.1; -; Genomic_DNA.
DR   RefSeq; XP_777392.1; XM_772299.1.
DR   EnsemblFungi; EAL22745; EAL22745; CNBB1930.
DR   GeneID; 4934285; -.
DR   KEGG; cnb:CNBB1930; -.
DR   EuPathDB; FungiDB:CNBB1930; -.
DR   eggNOG; KOG2084; Eukaryota.
DR   eggNOG; COG2940; LUCA.
DR   Proteomes; UP000001435; Chromosome 2.
DR   Proteomes; UP000001435; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR001214; SET_dom.
DR   Pfam; PF00856; SET; 1.
DR   PROSITE; PS50280; SET; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Methyltransferase; Nucleus;
KW   S-adenosyl-L-methionine; Transferase.
FT   CHAIN         1    449       Potential protein lysine
FT                                methyltransferase SET5.
FT                                /FTId=PRO_0000410283.
FT   DOMAIN       93    410       SET. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00190}.
SQ   SEQUENCE   449 AA;  50813 MW;  4E842F2DE3A972E3 CRC64;
     MKDLTAEAAI SPSDDNLLPA LASLREGHPD KGILKLLAQL KIDHPEWAVS EKRFRKALQL
     APCPGGGEAD PKEKALVADT GLDPSIDVKS IAPKVEVKMF AGGKGKGLVA KEELKQGEML
     WQEEPWIVTS DPGHYSLLTQ SMMCSQCFSL FARPSPPISV PCPHCTTAHF CNRLCYTKSL
     SSSHPPLLCP GLNPDASSLM NFIRKRGERS VEGVAKILAR WRGEREWDAK GKAEEMEKRI
     WKGMARVSQK RKEMERREWS YISKARMEEW HLIHIMLTNV LNPSPTHENY KPFQRLLISQ
     HPRRSKPVPL TEKEVKRWFS FESFLELLGL VGLNQEDSGG LYALHAHMNH SCEPNIQVRN
     LPKSYTPPTQ DTLPVNLPPP IQAGDRVSNK LTILARHEIQ PGEELTISYV NMKMSRDERR
     QALREGYGFW CACDRCMREK EQPNGEKAE
//
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